Active ingredient: Benzalkonium Chloride

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Benzalkonium Chloride uses


Pharmacological action

Benzalkonium Chloride is an antiseptic. This medication is a quaternary ammonium compound, belongs to the cationic surfactant. Benzalkonium Chloride has antimicrobial and antiviral activity against Neisseria gonorrhoeae, Chlamydia spp., Trichomonas vaginalis, Herpes simplex Type 2, Staphylococcus aureus, little active against Gardnerella vaginalis, Candida albicans, Haemophilus ducreyi and Treponema pallidum.

Benzalkonium Chloride is not active against Mycoplasma spp.

This medicine exerts spermicidal action which is due to the ability to damage the sperm membrane; inhibits sperm motility, disrupting electrolyte balance of the aqueous phase of cervical mucus.

Pharmacokinetics

Benzalkonium Chloride for external and local application is practically not absorbed.

Why is Benzalkonium Chloride prescribed?

For external use only. Topical solution - a primary and delayed primary wound treatment, prevention of secondary infection of wounds hospital strains of microorganisms, festering wounds, drainage of bone cavities following surgery for osteomyelitis.

Weight thick - superficial thermal burns, trophic ulcers, long-unhealed wounds of soft tissues (including infected), pyo-inflammatory skin diseases and diabetes mellitus; paraproctitis.

Tablets and capsules for intravaginal use, vaginal suppositories, creams, tampons - local contraception for women of reproductive age: for the presence of contraindications to the use of oral contraceptives or intrauterine devices, in the postpartum period, lactation, after the termination of pregnancy in premenopause period at irregular sexual life, omission or delay in receiving consistently used oral contraceptives.

Liquid concentrate - disinfection of facilities and medical products.

Dosage and administration

Topically. The solution was diluted with distilled water to make 1% aqueous solution, impregnated gauze dressings, napkins or tampons and put on the wound daily.

Mass is applied at the rate of 0.2-0.4 g/cm2 of wound surface, pre-clean the wound from the purulent discharge, necrotic tissue, or impose gauze or use turundas impregnated with drugs. The maximum daily dose is 50 g. Ligation is carried out daily, the course of treatment is 14 days.

Intravaginally (for contraception). Benzalkonium Chloride entered deeply into the vagina before coition; in case of repeated sexual intercourse it should be re-imposition of tablets, capsules, suppositories, creams; tampon can be removed not earlier than 3 h after the last sexual intercourse but no later than 24 hours after its installation (with repeated sexual acts for 1 day shift tampon is not required).

Concentrate Liquid. Benzalkonium Chloride used for disinfection after prior dilution with water.

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Benzalkonium Chloride side effects, adverse reactions

Contact dermatitis, candidiasis, vulvovaginal and allergic reactions.

With prolonged use of Benzalkonium Chloride it is possible a local irritation.

Benzalkonium Chloride contraindications

Hypersensitivity to Benzalkonium Chloride, contact dermatitis, malignant neoplasm of the skin; for intravaginal use - coleitis, ulceration and irritation of the mucous membrane of the vagina and uterus.

Using during pregnancy and breastfeeding

Benzalkonium Chloride has no negative impact on pregnancy. This medicine is not excreted in breast milk and it can be used during lactation.

Special instructions

To improve the efficiency it requires careful observance of the application method. Benzalkonium Chloride can be used in conjunction with a vaginal diaphragm or intrauterine device. You should avoid bathing or irrigation of the vagina with soapy water for 2 hours before and within 2 hours after sexual intercourse, outdoor toilet is only possible with clean water.

Benzalkonium Chloride is incompatible with soaps and other anionic surfactants as well as citrates, iodides, nitrates, permanganates, salicylates, silver salts and tartrates.

Benzalkonium Chloride drug interactions

Any substance introduced intravaginally can reduce local spermicidal action (including soaps and solutions containing it). Iodine solutions inactivate Benzalkonium Chloride.

Benzalkonium Chloride available forms, composition, doses:


Indications and Usages:

ATC codes:


ICD-10 codes:


Benzalkonium Chloride destination | category:


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Drugs with same active ingredients (Pharmaceutical companies):


References

  1. Dailymed."ECOLAB INC. (BENZALKONIUM CHLORIDE) SOLUTION [ECOLAB INC.]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. "Benzalkonium". https://pubchem.ncbi.nlm.nih.gov/su... (accessed August 28, 2018).
  3. "Benzalkonium - DrugBank". http://www.drugbank.ca/drugs/DB1110... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Benzalkonium Chloride?

Depending on the reaction of the Benzalkonium Chloride after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Benzalkonium Chloride not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Benzalkonium Chloride addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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Review

sdrugs.com conducted a study on Benzalkonium Chloride, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Benzalkonium Chloride consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

Visitor reports

Visitor reported useful

No survey data has been collected yet

Visitor reported side effects

No survey data has been collected yet

Visitor reported price estimates

No survey data has been collected yet

Visitor reported frequency of use

No survey data has been collected yet

Visitor reported doses

No survey data has been collected yet

One visitor reported time for results

What is the time duration Benzalkonium Chloride drug must be taken for it to be effective or for it to reduce the symptoms?
Most chronic conditions need at least some time so the dose and the drug action gets adjusted to the body to get the desired effect. The stastistics say sdrugs.com website users needed 1 week to notice the result from using Benzalkonium Chloride drug. The time needed to show improvement in health condition after using the medicine Benzalkonium Chloride need not be same for all the users. It varies based on other factors.
Visitors%
1 week1
100.0%

Visitor reported administration

No survey data has been collected yet

Two visitors reported age

Visitors%
46-601
50.0%
> 601
50.0%

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The information was verified by Dr. Rachana Salvi, MD Pharmacology

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