Pharma company: purepac pharmaceuticals
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List of purepac pharmaceuticals products:
- Acetaminophen; Codeine - This combination medication is used to help relieve mild to moderate pain. It contains a narcotic pain reliever (codeine) and a non-narcotic pain reliever (acetaminophen). Codeine works in the brain to change how your body feels and responds to pain. Acetaminophen can also reduce a fever. OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a...
- Acetaminophen; Codeine N3
- Acyclovir - Pharmacological action Acyclovir Pharma is an antiviral agent. Thymidine kinase of virus-infected cells actively converts acyclovir through a series of sequential reactions in the mono-, di- and triphosphate of acyclovir. The latter interacts with the viral DNA polymerase, and embedded in DNA, which is synthesized for new viruses. Thus it is formed a "defective" viral DNA which leads to suppression of replication of new generations of viruses. This mediciine acyclovir is active against...
- Allopurinol - Pharmacological action Allopurinol Laboratories is a medication that violates the synthesis of uric acid. This drug is a structural analog of hypoxanthine. It inhibits the enzyme xanthine oxidase, which is involved in the conversion of hypoxanthine to xanthine and xanthine to uric acid. This is due to decrease in the concentration of uric acid and its salts in body fluids and urine, which helps dissolve existing uric acid deposits and prevents their formation in tissues and kidney....
- Alprazolam - Pharmacological action Alprazolam is an anxiolytic drug (tranquilizer), a derivative of triazolo-benzodiazepine. This medication has anxiolytic, sedative, hypnotic, anticonvulsant, central muscle relaxant effect. The mechanism of action is to enhance the inhibitory effect of endogenous GABA in the CNS by increasing the sensitivity of the GABA-receptor mediator as a result of stimulation of benzodiazepine receptors located in the allosteric center of postsynaptic GABA-receptor activating...
- Aminophylline - SPL UNCLASSIFIED SECTION Aminophylline Injection, USP 25 mg/mL Aminophylline, Dihydrate (Equivalent to 19.7 mg/mL of Anhydrous Theophylline) ...
- Amitriptyline - Pharmacological action Amitriptyline is an antidepressant tricyclic group of compounds derived dibenzocycloheptadiene. The mechanism of antidepressant action is associated with an increased concentration of norepinephrine in the synapses and / or serotonin in the central nervous system depression due to reverse neuronal capture of these mediators. When anxiety and depressive states this medication reduces anxiety, agitation and depressive symptoms. Also this drug has some analgesic...
- Ampicillin - DESCRIPTION: Ampicillin for injectable suspension, veterinary is a broad-spectrum penicillin which has bactericidal activity against a wide range of common gram-positive and gram-negative bacteria. Each 25 g vial contains: 25 g ampicillin activity as ampicillin trihydrate, 90 mg methylparaben (as preservative), 10 mg propylparaben (as preservative), 200 mg lecithin, 500 mg povidone, 200 mg sodium chloride, 600 mg sodium...
- Aspirin, Butalbital, Caffeine
- Captopril - SPL UNCLASSIFIED SECTION CAPTOPRIL TABLETS, USP Rev. 03/16 Rx Only WARNING: FETAL TOXICITY • When pregnancy is detected, discontinue captopril tablets as soon as possible. • Drugs...
- Carbamazepine - WARNINGS SERIOUS DERMATOLOGIC REACTIONS AND HLA-B * 1502 ALLELE SERIOUS AND SOMETIMES FATAL DERMATOLOGIC REACTIONS, INCLUDING TOXIC EPIDERMAL NECROLYSIS (TEN) AND STEVENS-JOHNSON SYNDROME (SJS), HAVE BEEN REPORTED DURING TREATMENT WITH CARBAMAZEPINE. THESE REACTIONS ARE ESTIMATED TO OCCUR IN 1 TO 6 PER 10,000 NEW USERS IN COUNTRIES WITH MAINLY CAUCASIAN POPULATIONS, BUT THE RISK IN SOME ASIAN COUNTRIES IS ESTIMATED TO BE ABOUT 10 TIMES...
- Carbidopa; Levodopa
- Cefadroxil - SPL UNCLASSIFIED SECTION CEFADROXIL CAPSULES, USP Rev. 01/16 Rx Only To reduce the development of drug resistant bacteria and maintain the effectiveness of cefadroxil capsule and other antibacterial drugs, cefadroxil capsule should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. ...
- Cephalexin - 1 INDICATIONS & USAGE Cephalexin is a cephalosporin antibacterial drug indicated for the treatment of the following infections caused by susceptible isolates of designated bacteria: Respiratory tract infection ( 1.1 ) Otitis media ( 1.2 ) ...
- Chlordiazepoxide - An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal. [PubChem] Indication: For the management of anxiety disorders or for the short-term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety. Chlordiazepoxide has antianxiety, sedative, appetite-stimulating and weak analgesic actions. The drug seems to block EEG arousal...
- Chloroquine - The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses. [PubChem] Indication: For the suppressive treatment and for acute attacks of malaria due to P. vivax, P.malariae, P. ovale, and susceptible strains of P. falciparum, Second-line agent in treatment of Rheumatoid Arthritis Chloroquine is the prototype anti malarial drug, most...
- Chlorpheniramine - A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine. [PubChem] Indication: For the treatment of rhinitis, urticaria, allergy, common cold, asthma and hay fever. In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and...
- Chlorpromazine - The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine’s antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup. [PubChem] Indication: For the treatment of schizophrenia, control nausea and vomiting, For relief of restlessness and apprehension before...
- Chlorthalidone - Chlorthalidone is an oral antihypertensive/diuretic. It is a monosulfamyl diuretic that differs chemically from thiazide diuretics in that a double-ring system is incorporated in its structure. It is 2-chloro-5(1-hydroxy-3-oxo-1- isoindolinyl) benzenesulfonamide with the following structural formula: Molecular Formula: C 14 H 11 ClN 2 O 4 S Molecular Weight: 338.76 Chlorthalidone, USP is...
- Citalopram - Pharmacological action Citalopram is an antidepressant. The mechanism of action is associated with selective blockade of the inverse of neuronal serotonin in the synapses of neurons of the CNS. Citalopram lacks or has a very weak ability to bind to histamine, m-choline- and adrenoreceptors. Pharmacokinetics After oral administration C max of citalopram in plasma is achieved within 2-4 hours. The oral bioavailability is about 80%. Changes in plasma concentrations of citalopram are...
- Clonazepam - Pharmacological action Clonazepam is an antiepileptic drugs from the group of benzodiazepine derivatives. This medication has a pronounced anticonvulsant and central muscle relaxant, anxiolytic, sedative and hypnotic effects. Clonazepam strengthens the inhibitory effect of GABA on the transmission of nerve impulses. Anxiolytic effects of this drug is due to the influence on the amygdaloid complex of the limbic system and appears in reducing the emotional stress, reduce anxiety, fear,...
- Clonidine - Clonidine information Clonidine is a medicine that is meant to lower the patient's blood pressure. It achieves its purpose as it decreases the levels in which certain chemicals are found in the patient's blood. In this way, the veins and arteries are allowed to widen, enabling the heart to beat regularly. Clonidine indications Clonidine is normally used in the treatment of hypertension (also known as high blood pressure). But Clonidine can also be used for other purposes that have not...
- Clorazepate - A water-soluble benzodiazepine derivative effective in the treatment of anxiety. It has also muscle relaxant and anticonvulsant actions. [PubChem] Indication: For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Also used as adjunctive therapy in the management of partial seizures and for the symptomatic relief of acute alcohol withdrawal. Clorazepate is a member of the group of drugs called benzodiazepines. Pharmacologically, clorazepate has the...
- Cortisone
- Dextroamphetamine - BOXED WARNING AMPHETAMINES HAVE A HIGH POTENTIAL FOR ABUSE. ADMINISTRATION OF AMPHETAMINES FOR PROLONGED PERIODS OF TIME MAY LEAD TO DRUG DEPENDENCE AND MUST BE AVOIDED. PARTICULAR ATTENTION SHOULD BE PAID TO THE POSSIBILITY OF SUBJECTS OBTAINING AMPHETAMINES FOR NON-THERAPEUTIC USE OR DISTRIBUTION TO OTHERS, AND THE DRUGS SHOULD...
- Diazepam - SPL UNCLASSIFIED SECTION Fliptop Vial Rx only CIV WARNING: RISKS FROM CONCOMITANT USE WITH OPIOIDS Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death...
- Diclofenac - Pharmacological action NSAIDs, a derivative of phenylacetic acid, diclofenac has a pronounced anti-inflammatory, analgesic and mild antipyretic effect. The mechanism of action is associated with inhibition of COX activity - the main enzyme metabolism of arachidonic acid, which is a precursor of prostaglandins, which play a major role in the pathogenesis of inflammation, pain and fever. Analgesic effect is due to two mechanisms: peripheral (indirectly, through suppression of prostaglandin...
- Diflunisal - Cardiovascular Thrombotic Events Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use (see WARNINGS and PRECAUTIONS ). Diflunisal...
- Diltiazem - A benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions. It is also teratogenic. [PubChem] Indication: For the treatment of Hypertension Diltiazem, a benzothiazepine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Diltiazem is a non-dihydropyridine (DHP)member of the calcium channel blocker...
- Diphenhydramine - Pharmacological action Diphenhydramine Xepa-Soul Pattinson is a blocker of histamine H1-receptors. It has antiallergic activity, has a local anesthetic, antispasmodic and mild ganglion blocking action. When Diphenhydramine Xepa-Soul Pattinson administered orally diphenhydramine has a sedative and hypnotic effects, has a moderate antiemetic effect and has a central holinoliticheskoy activity. When applied externally it has antiallergic effect. Pharmacokinetics Diphenhydramine...
- Dipyridamole - DESCRIPTION PERSANTINE® (dipyridamole USP) is a platelet inhibitor chemically described as 2,2',2",2"'-[(4,8- Dipiperidinopyrimido[5,4- d ]pyrimidine-2,6-diyl)dinitrilo]-tetraethanol. It has the following structural formula: Dipyridamole is an odorless yellow crystalline powder, having a bitter taste. It is soluble in dilute acids, methanol and chloroform, and practically insoluble in water. PERSANTINE...
- Doxazosin - DESCRIPTION Doxazosin mesylate is a quinazoline compound that is a selective inhibitor of the alpha 1 subtype of alpha adrenergic receptors. The chemical name of doxazosin mesylate is 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl) piperazine methanesulfonate. The molecular formula for doxazosin mesylate is C 23 H 25 N 5 O 5 • CH 4 O 3 S and the molecular weight is 547.6. It has the following structure: ...
- Doxepin - Doxepin hydrochloride is a dibenzoxepin-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, doxepin does not affect mood or arousal, but may cause sedation. In depressed individuals, doxepin exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. Tertiary amine TCAs, such as doxepin and...
- Erythromycin - SPL UNCLASSIFIED SECTION Film-coated Tablets Rx only To reduce the development of drug-resistant bacteria and maintain the effectiveness of Erythromycin Tablets and other antibacterial drugs, Erythromycin Tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DESCRIPTION ...
- Etodolac - Cardiovascular Thrombotic Events Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use (see WARNINGS and ...
- Famotidine - DESCRIPTION The active ingredient in PEPCID* Registered trademark of Merck Sharp and Dohme Corp, a subsidiary of Merck & Co. Inc. and is used under license. (famotidine) is a histamine H 2 ‑receptor antagonist. Famotidine is N -(aminosulfonyl)-3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanimidamide. The empirical formula of famotidine is C 8 H 15 N 7 O 2 S 3 and its molecular weight is 337.43. Its structural...
- Fenoprofen - SPL UNCLASSIFIED SECTION Rx only Cardiovascular Risk Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. This risk may increase with duration of use. Patients with...
- Flurazepam - A benzodiazepine derivative used mainly as a hypnotic. [PubChem] Indication: For short-term and intermittent use in patients with recurring insomnia and poor sleeping habits Flurazepam, a benzodiazepine derivative, is a hypnotic agent which does not appear to decrease dream time as measured by rapid eye movements (REM). Furthermore, it decreases sleep latency and number of awakenings for a consequent increase in total sleep time.
- Fluvoxamine - Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder.Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised of approximately 35,000 patients. It was launched in the US in December 1994 and in Japan in June 1999. As of the end of 1995, more than 10 million patients worldwide...
- Folic Acid - SPL UNCLASSIFIED SECTION Rx only DESCRIPTION: Folic Acid Injection, USP is a sterile, nonpyrogenic solution of sodium folate (prepared by the addition of sodium hydroxide to folic acid) in Water for Injection intended for intramuscular (IM), intravenous (IV) or subcutaneous (SC) use. Folic Acid is a complex organic compound present in liver, yeast and other substances, which...
- Gabapentin - Pharmacological action Gabapentin is an antiepileptic drug. Chemical structure is similar to GABA fulfilling the function of the inhibitory neurotransmitter in the CNS. It is believed that the mechanism of action of Gabapentin is different from other anticonvulsants acting through GABA synapses (including valproate, barbiturates, benzodiazepines, inhibitors of GABA-transaminase, inhibitors of GABA capture, GABA agonists and prodrugs of GABA). In in vitro studies showed that Gabapentin is...
- Gemfibrozil - Gemfibrozil information Gemfibrozil is a drug which is usually prescribed along with a diet to people who have very high levels of serum triglycerides (triglycerides are fatty substances from the blood) and who are at a risk of developing pancreatitis (this is the inflammation of the pancreas). This medication may also be used in order to reduce the risk of developing coronary heart disease in people who have not responded to the other therapy options: weight loss, exercises, and diet and...
- Glyburide; Metformin - This combination medication is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes (non- insulin -dependent diabetes ). It may also be used with other diabetes medications. This product contains 2 medications. Glyburide belongs to the class of drugs known as sulfonylureas. It lowers blood sugar by causing the release of your body's natural insulin and by decreasing the amount of sugar that your liver makes. Metformin works by...
- Haloperidol - WARNING Increased Mortality in Elderly Patients with Dementia-Related Psychosis Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Analyses of seventeen placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1.6 to 1.7...
- Hydralazine - A direct-acting vasodilator that is used as an antihypertensive agent. [PubChem] Indication: For the treatment of essential hypertension, alone or as an adjunct. Also for the management of severe hypertension when the drug cannot be given orally or when blood pressure must be lowered immediately, congestive heart failure (in combination with cardiac glycosides and diuretics and/or with isosorbide dinitrate), and hypertension secondary to pre-eclampsia/eclampsia. A vasodilator, hydralazine works...
- Hydrochlorothiazide - Hydrochlorothiazide information Hydrochlorothiazide is an antihypertensive, diuretic drug that acts on the electrolyte reabsorption in the renal tubular mechanism increasing the excretion of chloride and sodium in equivalent amounts. The exact mechanism of its antihypertensive action is not known at this time. Hydrochlorothiazide indications Hydrochlorothiazide is typically employed for the treatment of patients suffering from hypertension, either as monotherapy or in combination with...
- Hydroxyzine - Hydroxyzine information This medication is made by Pfizer and is generically known as hydroxyzine hydrochloride and is available in tablet and syrup form. Hydroxyzine indications This drug is prescribed for the relief of anxiety and tension brought about by psychoneurosis. Hydroxyzine may also be used for the containment of pruritus due to allergic reactions such as chronic uticaria and contact dermatitis. Hydroxyzine may be used as a sedative when used as a premedication following...
- Ibuprofen - SPL UNCLASSIFIED SECTION Rx Only Cardiovascular Risk • NSAIDs may cause an increased risk of serious cardiovascular thrombotic events,...
- Indapamide - SPL UNCLASSIFIED SECTION 40-9191 Revised — November 2015 Rx Only DESCRIPTION Indapamide is an oral antihypertensive/diuretic. Its molecule contains both a polar sulfamoyl chlorobenzamide moiety and a lipid-soluble methylindoline moiety. It differs...
- Isoniazid - SPL UNCLASSIFIED SECTION Rev. 02/11 Rx Only WARNING Severe and sometimes fatal hepatitis associated with isoniazid therapy has been reported and may occur or may develop even after many months of treatment. The risk of developing hepatitis is age related. Approximate case rates by age are: less than 1 per 1,000 for persons under 20 years of age, 3 per 1...
- Isosorbide Mononitrate - DESCRIPTION monoket ® , an organic nitrate, is a vasodilator with effects on both arteries and veins. The empirical formula is C 6 H 9 NO 6 and the molecular weight is 191.14. The chemical name for monoket ® is 1,4:3,6-Dianhydro-D-glucitol 5-nitrate and the compound has the following structural formula: monoket ® is available in 10 mg and 20 mg tablets. Each tablet also contains as inactive ingredients: ...
- Lisinopril - WARNING: FETAL TOXICITY • When pregnancy is detected, discontinue lisinopril as soon as possible [see Warnings and Precautions (5.1) ]. • Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus [see ...
- Lisinopril; Hydrochlorothiazide - This medication is used to treat high blood pressure ( hypertension ). Lowering high blood pressure helps prevent strokes, heart attacks , and kidney problems. This product contains two medications: lisinopril and hydrochlorothiazide . Lisinopril is an ACE inhibitor and works by relaxing blood vessels so that blood can flow more easily. Hydrochlorothiazide is a "water pill" (diuretic) that causes you to make more urine, which helps your body get rid of extra salt and water. This...
- Lorazepam - DESCRIPTION Each mL of Lorazepam Concentrate, USP for oral administration contains: Lorazepam . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 mg Inactive Ingredients Lorazepam Oral Concentrate, USP contains polyethylene glycol, propylene glycol and triacetin. Lorazepam, an antianxiety agent, has the chemical formula, ...
- Lovastatin - DESCRIPTION Lovastatin, USP is a cholesterol lowering agent isolated from a strain of Aspergillus terreus . After oral ingestion, lovastatin, USP, which is an inactive lactone, is hydrolyzed to the corresponding β-hydroxyacid form. This is a principal metabolite and an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, which is an early and rate limiting step in the...
- Meprobamate - C-IV DESCRIPTION Meprobamate is a white powder with a characteristic odor and a bitter taste. It is slightly soluble in water, freely soluble in acetone and alcohol, and sparingly soluble in ether. The structural formula of meprobamate is: ...
- Metformin - Metformin is a biguanide antihyperglycemic agent used for treating non-insulin-dependent diabetes mellitus (NIDDM). It improves glycemic control by decreasing hepatic glucose production, decreasing glucose absorption and increasing insulin-mediated glucose uptake. Metformin is the only oral antihyperglycemic agent that is not associated with weight gain. Metformin may induce weight loss and is the drug of choice for obese NIDDM patients. When used alone, metformin does not cause hypoglycemia;...
- Methocarbamol - SPL UNCLASSIFIED SECTION METHOCARBAMOL TABLETS, USP Rev. 03/11 Rx Only DESCRIPTION: Methocarbamol Tablets, USP, a carbamate derivative of guaifenesin, are a central nervous system (CNS) depressant with sedative and musculoskeletal relaxant...
- Methyldopa - DESCRIPTION Methyldopa is an antihypertensive and is the L-isomer of alpha-methyldopa. It is levo-3-(3,4-dihydroxyphenyl)-2-methylalanine sesquihydrate. Methyldopa is supplied as tablets for oral administration, containing 250 mg and 500 mg of methyldopa. The amount of methyldopa is calculated on the anhydrous basis. Its molecular formula is C 10 H 13 NO 4 •1 1/2 H 2 O, with a molecular weight of 238.24, and its structural formula is: ...
- Methyldopa; Hydrochlorothiazide - This medication is used to treat high blood pressure ( hypertension ). Lowering high blood pressure helps prevent strokes, heart attacks , and kidney problems. This product contains 2 medications: methyldopa and hydrochlorothiazide . Methyldopa works by relaxing blood vessels so blood can flow more easily. Hydrochlorothiazide is a "water pill" (diuretic). It increases the amount of urine you make, especially when you first start the medication. It also helps to relax the blood...
- Methylphenidate - WARNING: ABUSE AND DEPENDENCE CNS stimulants, including COTEMPLA XR-ODT, other methylphenidate-containing products, and amphetamines, have a high potential for abuse and dependence. Assess the risk of abuse prior to prescribing, and monitor for signs of abuse and dependence while on therapy [see Warnings and Precautions (5.1) , Drug Abuse and Dependence (9.2 , 9.3) ] . ...
- Methyltestosterone - DESCRIPTION The androgens are steroids that develop and maintain primary and secondary male sex characteristics. Androgens are derivatives of cyclopentanoperhydrophenanthrene. Endogenous androgens are C-19 steroids with a side chain at C-17, and with two angular methyl groups. Testosterone is the primary endogenous androgen. In their active form, all drugs in the class have a 17-beta hydroxy group. 17-alpha alkylation (methylTESTOSTERone)...
- Metoclopramide - Boxed Warning 8/2017 Indications and Usage ( 1 ) 8/2017 Dosage and Administration, Dosage for Gastroesophageal Reflux ( 2.2 ) 8/2017 Dosage and Administration, Dosage for Acute and...
- Metoprolol - Pharmacological action Metoprolol is a cardioselective beta1-blocker without intrinsic sympathomimetic activity. This medication has antihypertensive, antianginal and antiarrhythmic effect. Metoprolol decreases automaticity of sinus node, reducing heart rate, slows AV-conduction, decreases myocardial contractility and excitability, reduces cardiac output, reduces myocardial oxygen demand. This drug inhibits the stimulatory effect of catecholamines on the heart during physical and...
- Mirtazapine - Suicidality and Antidepressant Drugs Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of mirtazapine tablets or any other antidepressant in a child, adolescent, or young adult must balance this risk with...
- Niacin - DESCRIPTION Niacin or nicotinic acid, a water-soluble B-complex vitamin and antihyperlipidemic agent, is 3-pyridinecarboxylic acid. It is a white, crystalline powder, sparingly soluble in water. It has the following structural formula: Each NIACOR ® Tablet, for oral administration, contains 500 mg of nicotinic acid. In addition, each tablet contains the following inactive ingredients: croscarmellose sodium, hydrogenated...
- Nifedipine - Pharmacological action Nifedipine is aSelective calcium channel blocker class II, a derivative of dihydropyridine. This medication inhibits the entry of calcium into cardiomyocytes and vascular smooth muscle cells. Nifedipine has antianginal and hypotensive action. This drug lowers the tone of vascular smooth muscle. Nifedipine dilates coronary and peripheral arteries, lowers blood pressure and slightly - myocardial contractility, reduces afterload and myocardial oxygen demand. This...
- Oxaprozin - WARNING: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS WARNING: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS See full prescribing information for complete boxed warning. ...
- Oxazepam - WARNING: RISKS FROM CONCOMITANT USE WITH OPIOIDS Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death (see Warnings, Drug Interactions). • Reserve concomitant prescribing of these drugs for use in patients for whom alternative treatment options are inadequate. • Limit dosages...
- Oxytetracycline - SPL UNCLASSIFIED SECTION VET one® Vetrimycin ™ 200 (oxytetracycline) 200 mg/mL Antibiotic ANADA 200-306, Approved by FDA Injection Each mL contains 200 mg of oxytetracycline base...
- Penicillin G Potassium - SPL UNCLASSIFIED SECTION To reduce the development of drug-resistant bacteria and maintain the effectiveness of Penicillin G Potassium and other antibacterial drugs, Penicillin G Potassium for Injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DESCRIPTION Buffered Pfizerpen (penicillin G potassium) for Injection is a...
- Penicillin V Potassium - SPL UNCLASSIFIED SECTION To reduce the development of drug-resistant bacteria and maintain the effectiveness of penicillin-VK and other antibacterial drugs, penicillin-VK should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DESCRIPTION Penicillin V is the phenoxymethyl analog of penicillin G. Penicillin V...
- Pentobarbital - A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236) Indication: For the short-term treatment of insomnia. Pentobarbital, a barbiturate, is used for the treatment of short term insomnia. It belongs...
- Pentoxifylline - Rx only DESCRIPTION Pentoxil ® (Pentoxifylline Extended-release Tablets, USP) for oral administration contain 400 mg of the active drug and the following inactive ingredients: D&C Red No. 27 Aluminum Lake, FD&C Blue No. 1 Aluminum Lake, hypromellose USP, magnesium stearate NF, polyethylene glycol NF, polysorbate 80 NF, povidone USP, silicon dioxide NF and titanium dioxide USP, in an extended-release formulation. Pentoxifylline is a tri-substituted xanthine derivative...
- Phentermine - A central nervous system stimulant and sympathomimetic with actions and uses similar to those of dextroamphetamine. It has been used most frequently in the treatment of obesity. [PubChem] Indication: For the treatment and management of obesity. Phentermine is indicated in the management of exogenous obesity as a short term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction. Phentermine hydrochloride is a sympathomimetic amine with pharmacologic activity similar...
- Pindolol - T1999-39 89003701 Visken ® (pindolol) tablets, USP Rx only Visken ® (pindolol), a synthetic beta-adrenergic receptor blocking agent with intrinsic sympathomimetic activity is 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol. Its structural formula is: Pindolol is a white to off-white odorless powder soluble in organic solvents and aqueous acids. Visken ® (pindolol)...
- Prazosin - Prazosin is a selective α-1-adrenergic receptor antagonist used to treat hypertension. It has also been used to decrease urinary obstruction and relieve symptoms associated with symptomatic benign prostatic hyperplasia. α1-Receptors mediate contraction and hypertrophic growth of smooth muscle cells. Antagonism of these receptors leads to smooth muscle relaxation in the peripheral vasculature and prostate gland. Prazosin has also been used in conjunction with cardiac glycosides and...
- Prednisolone - SPL UNCLASSIFIED SECTION For Oral Use in Dogs Only CAUTION Federal law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION Prednisolone, like methylprednisolone, is a potent anti-inflammatory steroid. Prednisolone, 11,17,21-trihydroxypregna-1,4-diene-3,20-dione, is a synthetic dehydrogenated...
- Prednisone - SPL UNCLASSIFIED SECTION Rx only DESCRIPTION Prednisone Tablets USP are available for oral administration containing either 1 mg, 2.5 mg, 5 mg, 10 mg, 20 mg or 50 mg of prednisone USP. Each tablet contains the following inactive ingredients: lactose monohydrate, magnesium stearate, microcrystalline cellulose, pregelatinized starch, sodium starch glycolate and stearic acid (1 mg, 2.5 mg, and 5 mg only). ...
- Propoxyphene - A narcotic analgesic structurally related to methadone. Only the dextro-isomer has an analgesic effect; the levo-isomer appears to exert an antitussive effect. [PubChem] Indication: For the relief of mild to moderate pain Propoxyphene, a synthetic opiate agonist, is structurally similar to methadone. Its general pharmacologic properties are those of the opiates as a group. The analgesic effect of propoxyphene is due to the d-isomer, dextropropoxyphene. It binds to the opiate receptors and leads...
- Propoxyphene; Acetaminophen
- Propranolol - Pharmacological action Propranolol is a non-selective beta-blocker. This medication has antihypertensive, antianginal and antiarrhythmic action. The hypotensive effect is associated with a decrease in minute volume of blood, sympathetic stimulation of peripheral vascular disease, decreased activity of the renin-angiotensin system (has a value in patients with initial hypersecretion of renin), sensitivity of baroreceptors of the aortic arch (not going to enhance their activity in response...
- Propranolol; Hydrochlorothiazide
- Propylthiouracil - SPL UNCLASSIFIED SECTION 40-9158 Revised — March 2016 Rx only WARNING Severe liver injury and acute liver failure, in some cases fatal, have been reported in patients treated with propylthiouracil. These reports of hepatic reactions...
- Quinidine - An optical isomer of quinine, extracted from the bark of the Cinchona tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular action potential, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission. [PubChem] Indication: For the treatment of ventricular pre-excitation and cardiac dysrhythmias Quinidine, a hydantoin...
- Ramipril - Ramipril information Ramipril belongs to the class of drugs classified as ACE inhibitors or Angiotensin-Converting-Enzyme inhibitor. Ramipril indications This product is a drug prescribed for the treatment of hypertension or high blood pressure, and for the prevention of heart failures succeeding heart attacks. Ramipril is also used for the prevention of heart attacks, stroke and other heart related problems. Ramipril warnings The medication is major allergen especially to patients...
- Reserpine - An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use. [PubChem] Indication: Foe the treatment of hypertension Reserpine is an adrenergic blocking agent used to treat mild to...
- Secobarbital - Secobarbital (marketed by Eli Lilly and Company under the brand names SeconalВ® and Tuinal) is a barbiturate derivative drug. It possesses anaesthetic, anticonvulsant, sedative and hypnotic properties. In the United Kingdom, it was known as Quinalbarbitone. Indication: For the Short-term treatment of intractable insomnia for patients habituated to barbiturates Secobarbital, a barbiturate, is used for the induction of anesthesia prior to the use of other general anesthetic agents and for...
- Spironolactone - SPL UNCLASSIFIED SECTION Rx only WARNING Spironolactone has been shown to be a tumorigen in chronic toxicity studies in rats (see Precautions ). Spironolactone should be used only in those conditions described under Indications and Usage ...
- Spironolactone; Hydrochlorothiazide
- Sulfisoxazole - A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms. [PubChem] Indication: For the treatment of severe, repeated, or long-lasting urinary tract infections, meningococcal meningitis, acute otitis media, trachoma, inclusion conjunctivitis, nocardiosis, chancroid, toxoplasmosis, malaria and other bacterial infections. Sulfisoxazole is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide...
- Temazepam - WARNING: RISKS FROM CONCOMITANT USE WITH OPIOIDS Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death ( see WARNINGS and Drug Interactions ). ...
- Tetracycline - Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane causing intracellular components to leak from bacterial cells. Indication: Used to treat...
- Ticlopidine - Ticlopidine is an effective inhibitor of platelet aggregation. The drug has been found to significantly reduce infarction size in acute myocardial infarcts and is an effective antithrombotic agent in arteriovenous fistulas, aorto-coronary bypass grafts, ischemic heart disease, venous thrombosis, and arteriosclerosis. [PubChem] Indication: Used to reduce the risk of thrombotic stroke (fatal or nonfatal) in patients who have experienced stroke precursors, and in patients who have had a completed...
- Tizanidine - Tizanidine is a short-acting drug for the management of spasticity. Tizanidine is an agonist at a2-adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, tizanidine has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of tizanidine are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce...
- Tolbutamide - DESCRIPTION Tolbutamide is an oral blood-glucose-lowering drug of the sulfonylurea class. Tolbutamide is a pure, white, crystalline compound which is practically insoluble in water. The chemical name is benzenesulfonamide, N-[(butylamino)-carbonyl]-4-methyl-. Its structure can be represented as follows: M.W. 270.35 C 12 H 18 N 2 O 3 S Tolbutamide is supplied as...
- Tolmetin - A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin. [PubChem] Indication: For the relief of signs and symptoms of rheumatoid arthritis and osteoarthritis, including the treatment of acute flares long-term management. Also for treatment of juvenile rheumatoid arthritis. Tolmetin is a nonsteroidal anti-inflammatory agent. Studies in animals have shown tolmetin to possess anti-inflammatory, analgesic and antipyretic activity....
- Tramadol - Pharmacological action Tramadol Karnataka Antibiotics & Pharmaceuticals is an opioid analgesic, a derivative of cyclohexanol. It is non-selective agonist of mu-, delta- and kappa-receptors in the CNS. Tramadol is a racemate (+) and (-) of isomers (50% / 50%) which in various ways are involved in analgesic effects. The isomer (+) is a pure agonist opioid receptors, it has low tropism and has a pronounced selectivity for different subtypes of receptors. The isomer (-) inhibiting neuronal...
- Trazodone - A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309) Indication: For the treatment of depression. Trazodone is an...
- Triamcinolone - A glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. (From Martindale, The Extra Pharmacopoeia, 30th ed, p739) Indication: For the treatment of perennial and seasonal allergic rhinitis. Triamcinolone and its derivatives are synthetic glucocorticoids that are used for their antiinflammatory or immunosuppressive properties.
- Triple Sulfa
- Verapamil - A calcium channel blocker that is a class IV anti-arrhythmia agent. [PubChem] Indication: For the treatment of hypertension, angina, and cluster headache prophylaxis. Verapamil is an L-type calcium channel blocker that also has antiarrythmic activity. The R-enantiomer is more effective at reducing blood pressure compared to the S-enantiomer. However, the S-enantiomer is 20 times more potent than the R-enantiomer at prolonging the PR interval in treating arrhythmias.
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The information was verified by Dr. Rachana Salvi, MD Pharmacology
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