MCalm Forte

Dosage and administration

Individual. It is recommended to use the minimum effective dose of MCalm Forte Aurobindo. The dose is corrected in the treatment process depending on the achieved effect and tolerability. If necessary, increase the dose should be increased gradually, first in the evening and then in the daytime reception.

The initial dose of MCalm Forte (Alprazolam) is 250-500 mcg 3 times / day, if necessary, it gradually increases to 4.5 mg / day.

For elderly or debilitated patients the initial dose is 250 mcg 2-3 / day, maintenance doses - 500-750 mcg / day, if necessary, taking into account the tolerance dose can be increased.

Cancellation or reduction of the dose of MCalm Forte (Alprazolam) should be done gradually by reducing the daily dose of no more than 500 mcg every 3 days; sometimes can needed even more slowly cancelling.

MCalm Forte (Alprazolam) side effects, adverse reactions

CNS: at the beginning of treatment (especially in elderly patients) drowsiness, fatigue, dizziness, decreased ability to concentrate, ataxia, disorientation, unsteady gait, slowing of mental and motor responses; rare - headache, euphoria, depression, tremors, memory loss, impaired coordination of movements, depressed mood, confusion, extrapyramidal dystonic reactions (involuntary movements, including for eyes), weakness, myasthenia gravis, dysarthria; in some cases - paradoxical reactions (aggressive flare, confusion, psychomotor agitation, fear, suicidal tendencies, muscle spasms, hallucinations, agitation, irritability, anxiety, insomnia).

Digestive system: possible dry mouth or excessive salivation, heartburn, nausea, vomiting, decreased appetite, constipation or diarrhea, abnormal liver function, elevated liver transaminases and alkaline phosphatase, jaundice.

Hematopoietic system: possible leukopenia, neutropenia, agranulocytosis (chills, pyrexia, sore throat, extreme tiredness or weakness), anemia, thrombocytopenia.

Urinary tract: possible urinary incontinence, urinary retention, renal failure, decreased or increased libido, dysmenorrhea.

Endocrine system: possible change in body weight, disturbances in libido, menstrual irregularities.

Cardiovascular system: possible decrease in blood pressure, tachycardia.

Allergic reactions: possible skin rash, itching.

Contraindications

Coma, shock, myasthenia gravis, angle-closure glaucoma, acute alcohol poisoning (with the weakening of the vital functions), narcotic analgesics, hypnotics and psychotropic drugs, chronic obstructive airways disease with incipient respiratory failure, acute respiratory failure, severe depression (suicidal tendencies may occur), pregnancy (especially the I trimester), lactation, childhood and adolescence to 18 years, increased sensitivity to benzodiazepines.

Using during pregnancy and breastfeeding

MCalm Forte (Alprazolam) has a toxic effect on the fetus and increases the risk of birth defects when used in the I trimester of pregnancy. The constant use during pregnancy can cause physical dependence with the development of withdrawal syndrome in the newborn. Reception at therapeutic doses in the later stages of pregnancy can cause neonatal CNS depression. Using of MCalm Forte (Alprazolam) immediately before birth or during labor can cause neonatal respiratory depression, decreased muscle tone, hypotension, hypothermia and a weak act of sucking (sucking flaccid syndrome baby).

It is possible to excretion of the benzodiazepines in breast milk that can cause drowsiness in the newborn and hinder feeding.

In experimental studies have been shown that MCalm Forte (Alprazolam) and its metabolites are excreted in breast milk.

Special instructions

Keep in mind that anxiety or conditions related to everyday stress usually does not require treatment with anxiolytics.

If you experience paradoxical reactions then stop taking the drug. During the period of treatment is unacceptable to use of alcoholic drinks. With caution use MCalm Forte for drivers of vehicles and people whose profession is associated with increased concentration.

MCalm Forte (Alprazolam) drug interactions

The simultaneous use of MCalm Forte (Alprazolam) with psychotropic, anticonvulsant medications and ethanol is observed enhancement inhibitory action MCalm Forte (Alprazolam) on the CNS.

The simultaneous use with blockers of histamine H2-receptor reduce the clearance of MCalm Forte (Alprazolam) and increase the inhibitory effect of MCalm Forte (Alprazolam) on the CNS; macrolide antibiotics reduce the clearance of MCalm Forte (Alprazolam).

The simultaneous use with hormonal oral contraceptives increased T1/2 of MCalm Forte (Alprazolam).

Simultaneous administration of MCalm Forte (Alprazolam) with dextropropoxyphene observed a more pronounced CNS depression than in combination with other benzodiazepines, as may increase the concentration of MCalm Forte (Alprazolam) in blood plasma.

Simultaneous treatment with digoxin increases the risk of intoxication by cardiac glycosides.

MCalm Forte (Alprazolam) increases the concentration of imipramine in plasma.

Simultaneous administration with itraconazole, ketoconazole increases the effects of MCalm Forte (Alprazolam).

Simultaneous administration with paroxetine may increases the effects of MCalm Forte (Alprazolam) due to the inhibition of its metabolism.

Fluvoxamine increases the concentration of MCalm Forte (Alprazolam) in plasma and risk of its side effects.

Simultaneous administration of MCalm Forte (Alprazolam) with fluoxetine may increase the concentration of MCalm Forte (Alprazolam) in plasma by decreasing its metabolism and clearance under the influence of fluoxetine which is accompanied by psychomotor disorders.

It can not be exclude the possibility of strengthening effect of MCalm Forte (Alprazolam) for simultaneous administration with erythromycin.

MCalm Forte in case of emergency / overdose

Symptoms: Varying degrees of CNS oppression (from sleepiness to coma) - drowsiness, confusion; in more severe cases (especially in patients receiving other drugs depressing the central nervous system or alcohol) - ataxia, decreased reflexes, hypotension, coma.

Treatment: induction of vomiting, gastric lavage, symptomatic therapy, monitor vital signs. In severe hypotension prescribed an injection of norepinephrine. Specific antidote is benzodiazepine receptor antagonist flumazenil (administration only in a hospital).

This medication may also be used for other medical purposes not stated herein.

Dosage and administration

When you order MCalm Forte Sanis Health, it should be taken exactly as prescribed by your doctor. Each tablet must be taken with a full glass of water.

For the oral concentrate of this medicine, it must be diluted before taking a dose. A dropper must adequately measure the amount of liquid to be diluted on the oral concentrate.

Each dose of MCalm Forte (Sertraline) should be taken at around the same time each day.

This drug can be taken with or without food.

MCalm Forte (Sertraline) is usually taken once a day and at the same time of each day. For the complete and exact dosage, refer to your doctor as other factors may also be considered such as body weight, age and the degree of illness.

When a dose of MCalm Forte (Sertraline) is missed, it is advisable to skip that dose and proceed to the next one. However, if the next dosage is many hours away, you could take the missed dose. It is not advisable to take the missed dose of this medication if you are near the time for the next dose, it is best if you entirely skip that dose and wait for the schedule of the next one.

MCalm Forte (Sertraline) side effects

The intake of MCalm Forte (Sertraline) depression medication may entail side effects depending on the susceptibility of the person. Some of the serious side effects tied to MCalm Forte (Sertraline) medication are:

Other less serious side effects of this medication include:

Contraindications

Concomitant use in patients taking monoamine oxidase inhibitors is contraindicated. Concomitant use in patients taking pimozide is contraindicated.

MCalm Forte (Sertraline) is contraindicated in patients with a hypersensitivity to MCalm Forte (Sertraline) or any of the inactive ingredients in this drug.

MCalm Forte (Sertraline) oral concentrate is contraindicated with ANT ABUSE (disulfiram) due to the alcohol content of the concentrate.

Using during pregnancy and breastfeeding

Before you buy MCalm Forte (Sertraline) online, understand that it belongs to the Pregnancy Category X type of drugs, which means that it is harmful to the unborn child. Taking MCalm Forte (Sertraline), especially during the last trimester of pregnancy, may cause birth defects and other medical complications for the mother. The active ingredient MCalm Forte (Sertraline) has not been tested to see if it passes through breast milk. Before deciding to breastfeed you should first consult your doctor.

Special instructions

While on MCalm Forte anti-depression medication, mental conditions may worsen - especially at the start of treatment due to the initial introduction of the medicine to your nervous system.

Expect the following conditions to worsen, especially at the first intake of MCalm Forte (Sertraline):

Your general mental condition should be monitored before, during and after treatment of MCalm Forte (Sertraline) as some undesired effects may occur when on MCalm Forte (Sertraline) medication.

Before taking MCalm Forte (Sertraline) Sanis Health, you should first tell your doctor if you any of the following medical conditions as taking this medicine may worsen it:

MCalm Forte (Sertraline) drug interactions

Never take MCalm Forte (Sertraline) if you are taking:

MCalm Forte in case of emergency / overdose

When symptoms of overdose are suspected, seek medical attention immediately. The symptoms of overdose may be characterized by: nausea; vomiting; tremors; seizures; extreme drowsy feeling; hyperactivity; enlarged and dilated pupils.