Indomethacin

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Indomethacin uses


Indomethacin information

Indomethacin is a non-steroidal anti-inflammatory drug, typically prescribed in order to manage symptoms such as pain, fever, swelling and stiffness. This medication acts as an inhibitor of prostaglandin production - prostaglandins are the agents that are known to induce these symptoms.

Indomethacin indications

There are several medical conditions for which Indomethacin may be prescribed, including rheumatoid arthritis, ankylosing spondylitis, arthritic gout, juvenile arthritis, osteoarthritis and psoriatic arthritis. Apart from these, this drug has shown positive results when prescribed for the treatment of Reiter's syndrome, Bartter syndrome and Paget's disease. Indomethacin may also be prescribed for patients that are suffering from pseudogout, pericarditis, dysmenorrheal, bursitis or tendonitis. This drug is also effective for the management of such affections as nephrogenic diabetes insipidus, hemicrania continua, paroxysmal hemicrania and migraine, but it may also be used in the management of symptoms such as pain and fever associated with malignancies. There may be other uses for this medication as well.

Indomethacin warnings

The intake of Indomethacin is not suitable in the case of patients that are suffering from an allergy to this drug, to any of its components, to Aspirin or to other non-steroidal anti-inflammatory medications. Also, this drug should not be employed in the treatment of patients with concurrent peptic ulcers or with severe preexisting liver or kidney damage. In the case of neonates with patent ductus arteriosus, Indomethacin should not be employed in the treatment of children of less than 2 years of age.

Caution should be employed in the treatment of patients suffering from Parkinson's disease, psychotic disorders or epilepsy as Indomethacin may worsen the symptoms of these conditions. Therapy with this medication may require special consideration when employed in the treatment of patients suffering from bleeding tendencies as Indomethacin may inhibit the aggregation of platelets. Frequent blood cell counts clinical evaluations are recommended in the case of patients with preexisting bone marrow damage.

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Indomethacin intake guidelines

It is highly recommended that the patient closely follows the Indomethacin intake guidelines that he or she has been given by the prescribing doctor. In many cases, regular physical examination of the patient may be required, in order to detect early signs of oedema or any possible side effects affecting the central nervous system. Blood pressure should be measured in order to check for hypertension. As part of the regular testing, blood cell counts, serum electrolyte measurements of the sodium, chloride and potassium and assessment of renal and liver functions should be performed, especially in the case of patients that are being administered Indomethacin in combination with a potassium-sparing diuretic or an ACE inhibitor; this is useful in order to detect or prevent development of kidney failure or hyperkalemia.

Indomethacin dosage

The exact Indomethacin dosage depends on the medical condition that the individual is being treated for. Apart from that, the examining health care professional will decide the appropriate dosage based on several factors such as the patient's medical history, his or her age as well as general health condition. The Indomethacin dosage may vary greatly from one patient to another, so it is highly recommended that you use the exact dosage that has been prescribed in your case.

Indomethacin overdose

Indomethacin has a high factor of acute toxicity in humans, and in some cases an overdose with this drug resulted in the death of the patient. As such, it is highly advised to take the medication dosage that has been prescribed for your case, and never take a higher dose.

Typical symptoms of a Indomethacin overdose include dizziness, drowsiness, mental confusion, severe headache, paraesthesia, nausea, vomiting and numbness of limbs. In some cases, severe gastrointestinal bleeding as well as cardiac arrest or cerebral oedema are possible.

Indomethacin missed dose

It is highly advised that you set up a regular intake schedule in order to lower the risks of missing a dose of your medication. In the case of Indomethacin, if you happen to miss a dose it is advised to take it as soon as you remember, unless it is almost time for another dose of the medication. If this is the case, you should completely skip the missed dose and continue with your regular intake schedule; you should bring the matter to the attention of your personal health care provider as soon as possible. He or she will assess the situation and decide on the appropriate course of action to take, if needed.

Indomethacin side effects

There are several side effects associated with a Indomethacin treatment. Treatment with this drug may lead to the appearance of peptic ulcers or other less severe gastrointestinal disturbances such as mild diarrhea, dyspepsia or heartburn. Due to the retention of lithium, patients following a treatment with Indomethacin have a higher risk of lithium toxicity. Hypertension, hyperkalemia and hypernatremia as well as oedema are also possible side effects of a therapy with this drug. In up to 20% of the cases, the patients may experience headaches, sometimes together with tinnitus, vertigo, dizziness, hearing loss or blurred vision. Photosensitivity and skin reactions have been reported. In rare cases, Indomethacin may cause severe damage to the bone marrow, severe or even lethal hepatitis or potentially fatal shock.

Indomethacin drug reactions

At this time, there is no exact information regarding the possible interactions between Indomethacin and other medications. It is advised that you consult with your personal health care professional and inform him or her about any other medication you are currently taking before starting a treatment with this drug.

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Indomethacin pharmaceutical active ingredients containing related brand and generic drugs:


Indomethacin available forms, composition, doses:

Price
Apo-Indomethacin 25 mg Capsule0.09 USD
Apo-Indomethacin 50 mg Capsule0.16 USD
Capsules, Extended Release; Oral; Indometacin 75 mg
Capsules, Sustained Release; Oral; Indometacin 75 mg
Capsules; Oral; Indometacin 25 mg
Capsules; Oral; Indometacin 50 mg
Indocin 50 mg suppository9.56 USD
Indocin i.v. 1 mg vial642.6 USD
Indocin sr 75 mg capsule2.92 USD
Indomethacin 1 mg vial600.0 USD
Indomethacin 25 mg capsule0.44 USD
Indomethacin 50 mg capsule0.65 USD
Indomethacin CR 75 mg capsule3.12 USD
Indomethacin powder2.57 USD
Injectable; Injection; Indometacin 1 mg
Novo-Methacin 25 mg Capsule0.09 USD
Novo-Methacin 50 mg Capsule0.16 USD
Nu-Indo 25 mg Capsule0.09 USD
Nu-Indo 50 mg Capsule0.16 USD
Ratio-Indomethacin 100 mg Suppository0.93 USD
Sandoz Indomethacin 100 mg Suppository0.93 USD
Sandoz Indomethacin 50 mg Suppository0.93 USD
Suspension; Oral; Indometacin 25 mg / 5 ml

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Indomethacin destination | category:


Indomethacin Anatomical Therapeutic Chemical codes:


Indomethacin pharmaceutical companies:


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References

  1. Dailymed."INDOMETHACIN CAPSULE, EXTENDED RELEASE [LAKE ERIE MEDICAL & SURGICAL SUPPLY DBA QUALITY CARE PRODUCTS LLC]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. Dailymed."INDOMETHACIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  3. "indomethacin". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Indomethacin?

Depending on the reaction of the Indomethacin after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Indomethacin not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Indomethacin addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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Review

sdrugs.com conducted a study on Indomethacin, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Indomethacin consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

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The information was verified by Dr. Rachana Salvi, MD Pharmacology

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