DRUGS & SUPPLEMENTS

GLZ Plus

Name: GLZ Plus drug & pharmaceuticals. GLZ Plus available forms, doses, prices
Creator: sdrugs.com
Published: 2021-11-11T10:10:10+00:00

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GLZ Plus uses

GLZ Plus consists of Gliclazide, Metformin.

Gliclazide:

GLZ Plus (Gliclazide) reviews

GLZ Plus (Gliclazide) is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor. Sulfonylureas also increase peripheral glucose utilization, decrease hepatic gluconeogenesis and may increase the number and sensitivity of insulin receptors. Sulfonylureas are associated with weight gain, though less so than insulin. Due to their mechanism of action, sulfonylureas may cause hypoglycemia and require consistent food intake to decrease this risk. The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals. GLZ Plus (Gliclazide) has been shown to decrease fasting plasma glucose, postprandial blood glucose and glycosolated hemoglobin (HbA1c) levels (reflective of the last 8-10 weeks of glucose control). GLZ Plus (Gliclazide) is extensively metabolized by the liver; its metabolites are excreted in both urine (60-70%) and feces (10-20%).

Indication: For the treatment of NIDDM in conjunction with diet and exercise.

GLZ Plus (Gliclazide) is a second generation sulphonylurea which acts as a hypoglycemic agent. It stimulates β cells of the islet of Langerhans in the pancreas to release insulin. It also enhances peripheral insulin sensitivity. Overall, it potentiates insulin release and improves insulin dynamics.

Metformin:

GLZ Plus (Metformin) reviews

GLZ Plus (Metformin) is a biguanide antihyperglycemic agent used for treating non-insulin-dependent diabetes mellitus (NIDDM). It improves glycemic control by decreasing hepatic glucose production, decreasing glucose absorption and increasing insulin-mediated glucose uptake. GLZ Plus (Metformin) is the only oral antihyperglycemic agent that is not associated with weight gain. GLZ Plus (Metformin) may induce weight loss and is the drug of choice for obese NIDDM patients. When used alone, GLZ Plus (Metformin) does not cause hypoglycemia; however, it may potentiate the hypoglycemic effects of sulfonylureas and insulin. Its main side effects are dyspepsia, nausea and diarrhea. Dose titration and/or use of smaller divided doses may decrease side effects. GLZ Plus (Metformin) should be avoided in those with severely compromised renal function (creatinine clearance < 30 ml/min), acute/decompensated heart failure, severe liver disease and for 48 hours after the use of iodinated contrast dyes due to the risk of lactic acidosis. Lower doses should be used in the elderly and those with decreased renal function. GLZ Plus (Metformin) decreases fasting plasma glucose, postprandial blood glucose and glycosolated hemoglobin (HbA1c) levels, which are reflective of the last 8-10 weeks of glucose control. GLZ Plus (Metformin) may also have a positive effect on lipid levels.

Indication: For use as an adjunct to diet and exercise in adult patients (18 years and older) with NIDDM. May also be used for the management of metabolic and reproductive abnormalities associated with polycystic ovary syndrome (PCOS).

GLZ Plus (Metformin) is an oral antihyperglycemic agent that improves glucose tolerance in patients with NIDDM, lowering both basal and postprandial plasma glucose. GLZ Plus (Metformin) is not chemically or pharmacologically related to any other class of oral antihyperglycemic agents. Unlike sulfonylureas, GLZ Plus (Metformin) does not produce hypoglycemia in either patients with NIDDM or healthy subjects and does not cause hyperinsulinemia. GLZ Plus (Metformin) does not affect insulin secretion.

GLZ Plus pharmaceutical active ingredients containing related brand and generic drugs:

GLZ Plus available forms, composition, doses:

Tablets; Oral; Gliclazide 80 mg; Metformin 500 mg

GLZ Plus destination | category:

Human:
Antidiabetic agents

GLZ Plus Anatomical Therapeutic Chemical codes:

A10BA02 - Metformin
A10BB09 - Gliclazide

GLZ Plus pharmaceutical companies:

Alembic

References

"metformin". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
"gliclazide". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
"gliclazide". http://www.drugbank.ca/drugs/DB0112... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming GLZ Plus?

Depending on the reaction of the GLZ Plus after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider GLZ Plus not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is GLZ Plus addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

Review

sdrugs.com conducted a study on GLZ Plus, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of GLZ Plus consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.