Cesbron

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Cesbron uses



NADA 140-973, Approved by FDA

For oral use in horses only

Caution:

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Caution:

Federal law prohibits the extralabel use of this drug in food animals.

Each mL contains:

Cesbron HCl 72.5 mcg

Description:

Cesbron (4-amino-alpha-[(tert-butylamino) methyl]-3, 5-dichlorobenzyl alcohol hydrochloride) is a beta-2-adrenergic agonist which provides bronchodilating properties as well as other effects, with minimum effect on the cardiovascular system. It is provided as a colorless, palatable syrup. Cesbron Syrup (clenbuterol hydrochloride) is antagonized by beta-adrenergic blocking agents.

Indications:

Cesbron Syrup (clenbuterol hydrochloride) is indicated for the management of horses affected with airway obstruction, such as occurs in chronic obstructive pulmonary disease (COPD).

Contraindications:

Cesbron Syrup antagonizes the effects of prostaglandin F2 alpha and oxytocin. Cesbron Syrup should not be used in pregnant mares near term. Because tachycardia may occur, Cesbron Syrup should not be used in horses suspected of having cardiovascular impairment.

Warning:

The effect on reproduction in breeding stallions and brood mares has not been determined. Treatment starting with dosages higher than the initial dose is not recommended.

Human Warnings:

Not for human use. Do not use in horses intended for human consumption. Keep out of the reach of children. In case of accidental ingestion, contact a physician immediately. Ingestion of Cesbron Syrup may cause undesirable reactions. Cesbron, like other beta adrenergic agonists, can produce significant cardiovascular effects in some people as evidenced by elevated pulse rate, blood pressure changes and/or ECG changes.

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Dosage and Administration:

Administer orally twice a day (b.i.d.). Initial dose is 0.5 mL/100 lbs body weight (0.8 mcg/kg) twice daily.

Dosage Schedule:

Initial

Dosage: administer 0.5 mL/100 lbs (0.8 mcg/kg) for 3 days (6 treatments);

If no improvement, administer 1.0 mL/100 lbs (1.6 mcg/kg) for 3 days (6 treatments);

If no improvement, administer 1.5 mL/100 lbs (2.4 mcg/kg) for 3 days (6 treatments);

If no improvement, administer 2.0 mL/100 lbs (3.2 mcg/kg) for 3 days (6 treatments);

If no improvement, horse is non-responsive to Cesbron and treatment should be discontinued.

Recommended duration of treatment at effective dose is 30 days. At the end of this 30-day treatment period, drug should be withdrawn to determine recurrence of signs. If signs return, the 30-day treatment regimen may be repeated. If repeating treatment, the step-wise dosage schedule should be repeated.

Directions for Administration:

Remove safety cap and seal; replace with enclosed plastic dispensing cap. Remove cover from dispensing tip and connect syringe (without needle). Draw out appropriate volume of Cesbron Syrup. Administer orally to the horse. Replace cover on dispensing tip to prevent leakage.

Dosage Calculation Chart


Lbs. Body

Weight


mL/treatment

at 0.5 mL/100#

(0.8 mcg/kg)


mL/treatment

at 1.0 mL/100#

(1.6 mcg/kg)


mL/treatment

at 1.5 mL/100#

(2.4 mcg/kg)


mL/treatment

at 2.0 mL/100#

(3.2 mcg/kg)


500

600

700

800

900

1000

1100

1200

1300

1400

1500

1600

1700

1800


2.5

3.0

3.5

4.0

4.5

5.0

5.5

6.0

6.5

7.0

7.5

8.0

8.5

9.0


5.0

6.0

7.0

8.0

9.0

10.0

11.0

12.0

13.0

14.0

15.0

16.0

17.0

18.0


7.5

9.0

10.5

12.0

13.5

15.0

16.5

18.0

19.5

21.0

22.5

24.0

25.5

27.0


10.0

12.0

14.0

16.0

18.0

20.0

22.0

24.0

26.0

28.0

30.0

32.0

34.0

36.0


Administer two treatments per day.

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Precaution:

The safety cap should be placed on the bottle when not in use.

Adverse Reactions:

Mild sweating, muscle tremor, restlessness, urticaria and tachycardia may be observed in some horses during the first few days of treatment. May cause elevated creatine kinase (CK) serum levels. Ataxia was observed in 3 out of 239 horses (1.3%) in clinical studies. To report suspected adverse reactions, to obtain a Material Safety Data Sheet (MSDS), or for technical assistance, call 1-866-638-2226.

How Supplied:

Cesbron Syrup is available in 100 mL, 330 mL and 460 mL plastic bottles containing 72.5 mcg Cesbron HCl per mL.

NDC 0010-3017-02 - 100 mL

NDC 0010-3017-03 - 330 mL

NDC 0010-3017-04 - 460 mL

Storage:

Store at or below 25°C (77°F). Avoid freezing.

Cesbron is a registered trademark of Boehringer Ingelheim Vetmedica GmbH.

Manufactured for:

Boehringer Ingelheim Vetmedica, Inc.

St. Joseph, MO 64506 U.S.A.

301704-04

090330771/1

330 mL Display Carton – Front, Top and Side Panel

Picture of 330 mL display carton front, top and side panel.

330 mL Display Carton – Back and Side Panel

Picture of 330 mL display carton - back and side panel.
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Cesbron pharmaceutical active ingredients containing related brand and generic drugs:


Cesbron available forms, composition, doses:


Cesbron destination | category:


Cesbron Anatomical Therapeutic Chemical codes:


Cesbron pharmaceutical companies:


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References

  1. Dailymed."VENTIPULMIN (CLENBUTEROL) SYRUP [BOEHRINGER INGELHEIM VETMEDICA, INC.]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. "clenbuterol". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
  3. "clenbuterol". http://www.drugbank.ca/drugs/DB0140... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Cesbron?

Depending on the reaction of the Cesbron after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Cesbron not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Cesbron addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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Review

sdrugs.com conducted a study on Cesbron, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Cesbron consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

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The information was verified by Dr. Rachana Salvi, MD Pharmacology

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