DRUGS & SUPPLEMENTS

AZ-Oral

Name: AZ-Oral drug & pharmaceuticals. AZ-Oral available forms, doses, prices
Creator: sdrugs.com
Published: 2021-11-11T10:10:10+00:00

Rating: 1 - 1 review(s)

What are the side effects you encounter while taking this medicine?

AZ-Oral uses

Pharmacological action
Pharmacokinetics
Why is AZ-Oral prescribed?
Dosage and administration
AZ-Oral side effects, adverse reactions
Contraindications
Using during pregnancy and breastfeeding
Special instructions
AZ-Oral drug interactions
AZ-Oral reviews

Pharmacological action

AZ-Oral is a macrolide antibiotic of azalides group. AZ-Oral inhibits RNA-dependent protein synthesis of sensitive microorganisms.

It active against gram-positive bacteria: Staphylococcus aureus, Streptococcus spp. ; gram-negative bacteria: Haemophilus influenzae, Haemophilus parainfluenzae, Haemophilus ducreyi, Moraxella catarrhalis, Escherichia coli, Bordetella pertussis, Bordetella parapertussis, Borrelia burgdorferi, Neisseria gonorrhoeae, Campylobacter spp., Legionella pneumophila; anaerobic bacteria: Bacteroides fragilis.

Pharmacokinetics

AZ-Oral rapidly absorbed from the gastrointestinal tract. Ingestion reduces the absorption of AZ-Oral. C_max in plasma is reached after 2-3 hours. This medicine rapidly distributed in tissues and biological fluids. 35% of the AZ-Oral is metabolized in the liver by demethylation. More than 59% is excreted in the bile in unchanged form, about 4.5% in the urine in unchanged form.

Why is AZ-Oral prescribed?

Infectious-inflammatory diseases caused by microorganisms susceptible to AZ-Oral, including bronchitis, pneumonia, infections of skin and soft tissue, otitis media, sinusitis, pharyngitis, tonsillitis, gonorrheal and non gonorrheal urethritis and / or cervicitis, Lyme disease.

Dosage and administration

Dosage of AZ-Oral is setted individually according to nosology, disease severity and sensitivity of the pathogen. Dosage for adults for oral administration is 0.25-1 g 1 time/day; for children - 5-10 mg/kg 1 time/day. The duration of administration is 2-5 days.

AZ-Oral side effects, adverse reactions

Digestive system: nausea, vomiting, flatulence, diarrhea, abdominal pain, transient elevation of liver enzymes, rarely - cholestatic jaundice.

Allergic reactions: rarely - a skin rash, angioedema, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis.

Dermatological reactions: rarely - photosensitization.

CNS: dizziness, headache, rarely - drowsiness, weakness.

Hematopoietic system: rarely - leukopenia, neutropenia, thrombocytopenia.

Cardiovascular system: rarely - chest pain.

Urogenital system: vaginitis, rarely - candidiasis, nephritis, increased residual nitrogen urea.

Other: rarely - hyperglycemia, arthralgia.

Contraindications

Hypersensitivity to AZ-Oral and other macrolide antibiotics.

Using during pregnancy and breastfeeding

AZ-Oral crosses the placental barrier. Use in pregnancy only in cases where the intended benefits to the mother outweighs the potential risk to the fetus.

If necessary to use AZ-Oral in the lactation period should solve the issue of termination of breastfeeding.

Special instructions

AZ-Oral not recommended for use in patients with compromised liver function.

AZ-Oral uses with careful with impaired renal function.

This medication should be taken at least 1 hour before or 2 hours after eating or taking of antacids.

AZ-Oral drug interactions

Simultaneous administration of AZ-Oral with these drugs and medications may has followed effects:

ergot alkaloids: can not been exclude the risk of ergotism;

warfarin: there was described amplification effect of warfarin;

digoxin or digitoxin: may be significantly increase the concentration of cardiac glycosides in plasma and risk of glycoside intoxication;

disopyramide: described a case of ventricular fibrillation;

lovastatin: there was describes some cases of rhabdomyolysis;

AZ-Oral with rifabutin increases risk of neutropenia and leukopenia;

cyclosporine: disturbed metabolism of cyclosporine which increases the risk of adverse and toxic reactions caused by cyclosporine

AZ-Oral pharmaceutical active ingredients containing related brand and generic drugs:

Azithromycin Dihydrate

AZ-Oral available forms, composition, doses:

Capsules; Oral; Azithromycin Dihydrate 250 mg
Capsules; Oral; Azithromycin Dihydrate 500 mg
Suspension; Oral; Azithromycin Dihydrate 200 mg / 5 ml

AZ-Oral destination | category:

Human:
Macrolide antibiotics

AZ-Oral Anatomical Therapeutic Chemical codes:

J01FA10 - Azithromycin
S01AA26 - Azithromycin

AZ-Oral pharmaceutical companies:

References

Dailymed."ZITHROMAX (AZITHROMYCIN DIHYDRATE) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [PFIZER LABORATORIES DIV PFIZER INC]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
Dailymed."AZITHROMYCIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
"azithromycin". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming AZ-Oral?

Depending on the reaction of the AZ-Oral after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider AZ-Oral not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is AZ-Oral addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

Review

sdrugs.com conducted a study on AZ-Oral, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of AZ-Oral consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.