Mirapront

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Mirapront uses


What is Phentermine?

Mirapront is an appetite suppressant of a pharmacological group of amphetamines and phenethylamines. This medication was approved to help reduce weight in obese patients for short-term use and combination with exercise, diet and behavior changes. It usually prescribed to individuals who have health risks due to their weight. This active ingredient phentermine is manufactured and distributed in various countries under different trade brand and generic names, for example: Adipex-P (Teva), Ionamin (Celltech), Acxion (Investigacion Farmaceutica), Fastin (GlaxoSmithKline), Duromine (iNova, Douglas Pharmaceuticals), Panbesy (Eurodrug Laboratories), Phentermine (KVK-TECH), Phentermine (Eon Labs), etc. In several countries (such as the USA, Canada, Australia) this drug is a controlled substance because it can cause addiction.

Pharmacological action

Phentermine acts on the brain neurotransmitters. Mirapront is a central stimulant and an isomer of methamphetamine. It stimulates neurons to release a particular group of neurotransmitters known as catecholamines among which are dopamine, epinephrine (also called adrenaline) and norepinephrine. The appetite suppression activity of these compounds is due to its action on the central nervous system. This mechanism of action is similar to other stimulant appetite suppressants such as diethylpropion and phendimetrazine. The neurotransmitters signal the alert response which also stops the hunger.

Why is Mirapront prescribed?

Phentermine is used to reduce body weight in obese or overweight patients. Often it prescribed in a regimen of weight reduction based on exercise, behavioral modification, and caloric restriction in the management of exogenous obesity for obese or overweight patients with the presence of other risk factors. Mirapront works by directly affecting the area of the brain that controls your appetite making you feel less hungry.

Dosage and administration

It is recommended to use phentermine only in the short term (usually about 12 weeks) and then other non-pharmacological strategies for weight loss and healthy dieting and exercise. However, recommendations limiting its use for short-term treatment are controversial. One reason for the restriction to 12 weeks is drug tolerance, as phentermine loses its appetite-suppressing effects after the body adjusts. On the contrary, it has been shown that this drug did not lose its effect in a trial of 36 weeks. Due to the risk of insomnia, it is recommended taking phentermine before breakfast or 1-2 hours later.

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Mirapront side effects, adverse reactions

Generally, phentermine is relatively well tolerated but can cause some side effects because it releases catecholamines. Among the most common effects include: tachycardia, elevated blood pressure, palpitations, nervousness, irritability and insomnia. Additionally, if Mirapront is taken for long term, it may develop euphoria and addiction. Other less common side effects include blurred vision, changes in sex drive, clumsiness, confusion, diarrhea, dizziness, dry mouth, headache, irregular heartbeat, nausea or vomiting, psychosis, skin rash or itching, stomach pain, fatigue and bad taste.

Contraindications

The following people should not use phentermine:

  • Allergy to any ingredient of Mirapront containing pharmaceutical form (usually capsules or tablets) or other sympathomimetic (eg, pseudoephedrine).
  • Taking dexfenfluramine, fenfluramine, furazolidone, guanadrel, guanethidine, or have taken of mono-amine oxidase inhibitors (MAOIs) (eg., phenelzine) in the last 14 days.
  • With high blood pressure or moderate hyperthyroidism, glaucoma, heart or circulatory disease, or severe narrowing of blood vessels.
  • Who are in a state of agitation or have a history of alcohol or drug abuse.

    Mirapront using during pregnancy and breastfeeding

    There is no data whether phentermine can cause fetal harm when administered to a pregnant woman or can affect reproductive capacity. Thats why rgis drugs should be given to a pregnant woman only if clearly needed.

    Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

    Safety and effectiveness of Mirapront in pediatric patients have not been established.

    Special instructions

    You healthcare professional should be informed of the following conditions:

  • If you are pregnant or plan to become pregnant or if you are breastfeeding (lactation).
  • If you are taking prescription or nonprescription medications, herbal preparations or dietary supplements.
  • If you have allergies to medicines, foods or other substances.
  • If you have a brain disorder or spinal cord, narrowing of the arteries, high blood pressure (hypertension), diabetes or high cholesterol or lipids.

    Phentermine drug interactions

    The following drugs can interact with Mirapront:

  • Dexfenfluramine, fenfluramine, furazolidone, or inhibitors of MAO (eg., phenelzine) because the risk of serious side effects such as headaches, high blood pressure, low pulse, elevated temperature or fatal lung problems.
  • Inhibitors of serotonin reuptake (such as fluoxetine).
  • Guanadrel or guanethidine because their effectiveness may be decreased by phentermine.

    Mirapront in case of emergency / overdose

    In case of overdose of Mirapront, call your local poison control center or local emergency services.

    Manifestations of acute overdosage with phentermine include restlessness, hyperreflexia, tremor, confusion, assaultiveness, rapid respiration, hallucinations, panic states. Fatigue and depression usually follow the central stimulation. Cardiovascular effects include hypertension or hypotension, arrhythmia, and circulatory collapse. Gastrointestinal symptoms include vomiting, nausea, diarrhea and abdominal cramps. Fatal poisoning usually terminates in convulsions and coma.

    Management of acute phentermine intoxication is largely symptomatic and includes lavage and sedation with a barbiturate. Hemodialysis or peritoneal dialysis is ineffective and not recommended in this regard.

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    Mirapront pharmaceutical active ingredients containing related brand and generic drugs:


    Mirapront available forms, composition, doses:


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    Mirapront Anatomical Therapeutic Chemical codes:


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    Frequently asked Questions

    Can i drive or operate heavy machine after consuming Mirapront?

    Depending on the reaction of the Mirapront after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Mirapront not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

    Is Mirapront addictive or habit forming?

    Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

    Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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    Review

    sdrugs.com conducted a study on Mirapront, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Mirapront consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

    Visitor reports

    Three visitors reported useful

    How is the drug Mirapront useful in reducing or relieving the symptoms? How useful is it?
    According to the survey conducted by the website sdrugs.com, there are variable results and below are the percentages of the users that say the medicine is useful to them and that say it is not helping them much. It is not ideal to continue taking the medication if you feel it is not helping you much. Contact your healthcare provider to check if there is a need to change the medicine or if there is a need to re-evaluate your condition. The usefulness of the medicine may vary from patient to patient, depending on the other diseases he is suffering from and slightly depends on the brand name.
    Visitors%
    Useful3
    100.0%

    Two visitors reported side effects

    Did you get side effects while taking the Mirapront drug, or were there no side effects?
    According to the survey conducted by website sdrugs.com users, the below-mentioned percentages indicate the number of people experiencing the side effects and the number of people not experiencing the side effects when taking Mirapront medicine. Every drug produces minimal side effects, and they are negligible most times, when compared to the desired effect [use] of the medicine. Side effects depend on the dose you are taking, any drug interactions that happen when you are on other medications, if the patient is sensitive, and other associated conditions. If you cannot tolerate the side effects, consult your doctor immediately, so he can either adjust the dose or change the medication.
    Visitors%
    It has side effects1
    50.0%
    No side effects1
    50.0%

    One visitor reported price estimates

    What is your opinion about drug cost? Did you feel the cost is apt, or did you feel it is expensive?
    The report given by the sdrugs.com website users shows the following figures about several people who felt the medicine Mirapront is expensive, and the medicine is not expensive. The results are mixed. The perception of the cost of the medicine to be expensive or not depends on the brand name of the medicine, country, and place where it is sold, and the affordability of the patient. You can choose a generic drug in the place of the branded drug to save the cost. The efficiency of the medicine will not vary if it is generic or a branded one.
    Visitors%
    Not expensive1
    100.0%

    Two visitors reported frequency of use

    How often in a day do you take the medicine?
    Are you taking the Mirapront drug as prescribed by the doctor?

    Few medications can be taken Once in a day more than prescribed when the doctor's advice mentions the medicine can be taken according to frequency or severity of symptoms. Most times, be very careful and clear about the number of times you are taking the medication. The report of sdrugs.com website users about the frequency of taking the drug Mirapront is mentioned below.
    Visitors%
    Once in a day2
    100.0%

    Five visitors reported doses

    What is the dose of Mirapront drug you are taking?
    According to the survey conducted among sdrugs.com website users, the maximum number of people are using the following dose 11-50mg. Few medications come in only one or two doses. Few are specific for adult dose and child dose. The dose of the medicine given to the patient depends on the severity of the symptom/disease. There can be dose adjustments made by the doctor, based on the progression of the disease. Follow-up is important.
    Visitors%
    11-50mg2
    40.0%
    51-100mg2
    40.0%
    1-5mg1
    20.0%

    One visitor reported time for results

    What is the time duration Mirapront drug must be taken for it to be effective or for it to reduce the symptoms?
    Most chronic conditions need at least some time so the dose and the drug action gets adjusted to the body to get the desired effect. The stastistics say sdrugs.com website users needed > 3 month to notice the result from using Mirapront drug. The time needed to show improvement in health condition after using the medicine Mirapront need not be same for all the users. It varies based on other factors.
    Visitors%
    > 3 month1
    100.0%

    Visitor reported administration

    No survey data has been collected yet

    Fourteen visitors reported age

    Visitors%
    > 607
    50.0%
    46-606
    42.9%
    30-451
    7.1%

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    The information was verified by Dr. Rachana Salvi, MD Pharmacology

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