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DRUGS & SUPPLEMENTS
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Indication: For the treatment of severe hypertension and in the topical treatment (regrowth) of androgenic alopecia in males and females and stabilisation of hair loss in patients with androgenic alopecia.
Minoxidil is an orally effective direct acting peripheral vasodilator that reduces elevated systolic and diastolic blood pressure by decreasing peripheral vascular resistance. Minoxidil is also used topically to treat androgenetic alopecia. Microcirculatory blood flow in animals is enhanced or maintained in all systemic vascular beds. In man, forearm and renal vascular resistance decline; forearm blood flow increases while renal blood flow and glomerular filtration rate are preserved. The predominant site of Minoxidil action is arterial. Venodilation does not occur with Minoxidil; thus, postural hypotension is unusual with its administration. The antihypertensive activity of Minoxidil is due to its sulphate metabolite, Minoxidil sulfate.
Minoxidil is a drugs for the treatment of hair loss. This medication has a stimulating effect on hair growth in men and women with androgenetic alopecia. The appearance of signs of hair growth observed after 4 months or more of taking the drug 2 times / day. The beginning and the severity of the effect may vary in different patients. After the abolition of Minoxidil new hair growth stops, and after 3-4 months may restore the original appearance.
The exact mechanism of action of Minoxidil as a hair growth stimulant in patients with androgenic alopecia is unknown.
When used systemically this medicine has a vasodilating action. In controlled clinical studies after topical usage Minoxidil in patients with normal as well as with high blood pressure was not observed systemic side effects associated with systemic absorption of this drug.
When used topically Minoxidil is poorly absorbed through normal intact skin: an average of 1.4% (0.3-4.5%) of the total applied dose enters the systemic blood circulation. For topical osage a concentration of Minoxidil in the serum is determined by its rate of absorption through the skin. After the termination of this medication usage approximately 95% of Minoxidil subjected to systemic absorption, is excreted in 4 days.
Androgenic alopecia in men and women.
Minoxidil is applied to the skin of the scalp in a dose of 2 times / day (in the morning and evening).
Dermatological reactions: often - redness, itching, peeling of the skin of the scalp; in some cases - hypertrichosis.
May be increase hair loss during the transition from the resting phase to the phase of hair growth (this is a temporary phenomenon can be observed after 2-6 weeks after initiation of therapy and gradually, over 2 weeks, stop).
Cardiovascular system: in some cases - hypotension.
Children and teens under 18; redness, inflammation, infection, pain of the scalp (including the sunburn); hypersensitivity to Minoxidil.
Minoxidil is should not be used during pregnancy and lactation.
When the systemic side effects appear (retrosternal pain, palpitations, dizziness, decreased blood pressure, sudden weight gain, swelling of hands and / or legs), as well as redness and irritation at the site of rubbing Minoxidil should be discontinued and if necessary, prescribed the appropriate therapy.
In some patients after using Minoxidil observed changes in color and texture of hair.
With the simultaneous application of Minoxidil to the skin and drugs for external use, containing tretinoin, anthralin / dithranol may increase the absorption of Minoxidil.
Symptoms: excessive vasodilation, marked hypotension, chest pain, tachycardia or arrhythmia, movement (stiffness or trembling of hands, feet, head), sodium and water retention.
Treatment: symptomatic and supportive therapy - the IV introduction of saline solution; when hypotension - phenylephrine, angiotensin II, vasopressin, dopamine (do not use sympathomimetics, including norepinephrine and epinephrine).
Price | |
Aerosol, Foam; Topical; Minoxidil 5% | |
Injectable; Injection; Minoxidil 50 mg / ml | |
Loniten 10 mg Tablet | 1.52 USD |
Loniten 2.5 mg Tablet | 0.39 USD |
Lotion; Topical; Minoxidil 3% | |
Minoxidil 10 mg tablet | 1.32 USD |
Minoxidil 2.5 mg tablet | 0.7 USD |
Minoxidil powder | 2.07 USD |
Rogaine 5 % foam | 0.27 USD |
Rogaine ex-str starter kit | 28.32 USD |
Solution; Topical; Minoxidil 2% | |
Solution; Topical; Minoxidil 5% | |
Tablets; Oral; Minoxidil 10 mg | |
Tablets; Oral; Minoxidil 2.5 mg | |
Tablets; Oral; Minoxidil 5 mg |
Depending on the reaction of the Minoxidil after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Minoxidil not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.
Is Minoxidil addictive or habit forming?Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
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The information was verified by Dr. Rachana Salvi, MD Pharmacology