Fludizol

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Fludizol uses


Pharmacological action

Fludizol is an antifungal drug from the group of triazole derivatives. Inhibits the synthesis of ergosterol disrupting the permeability of the cell wall. This medication is active against Candida, Microsporum, Cryptococcus neoformans, Trichophyton.

Pharmacokinetics

Fludizol is well absorbed after oral administration. Simultaneous ingestion does not affect absorption. The bioavailability is 90%. Fludizol is widely distributed in tissues and organs of the body. Its concentration in breast milk, joint fluid, saliva, sputum, vaginal secretions and peritoneal fluid are similar to those in blood plasma. The concentration in the cerebrospinal fluid is 50-90% of the level in blood plasma, regardless of the presence of inflammation of the meninges. In the stratum corneum, epidermis, dermis and sweat fluid concentrations reach values exceeding the concentration in blood plasma. T1/2 is 30 h. Fludizol is excreted by the kidneys, 80% of the administered dose in an unmodified form.

Why is Fludizol prescribed?

Cryptococcosis, systemic candidiasis, candidiasis of the mucous membranes, vaginal candidiasis, prevention of fungal infections in patients with lowered immunity (including AIDS patients). Fungal infections of skin, including athlete's foot, body, groin, pityriasis versicolor, onychomycosis. Deep endemic mycoses, including coccidioidomycosis, paracoccidioidomycosis, sporotrichosis and histoplasmosis in patients with normal immunity.

Dosage and administration

Dosing regimen of Fludizol is individual. This medication is prescribed for oral and IV administration. Depending on the testimony of the daily dose is 50-400 mg, the multiplicity of application is 1 times / day. If impaired renal function the dose of Fludizol should be reduced.

Fludizol side effects, adverse reactions

Digestive system: nausea, abdominal pain, diarrhea, flatulence.

CNS: headache, dizziness.

Allergic reactions: skin rash, anaphylactic reactions.

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Fludizol contraindications

Pregnancy, children up to age 1 year, increased sensitivity to Fludizol and triazole compounds.

Using during pregnancy and breastfeeding

Fludizol is contraindicated during pregnancy and lactation.

If necessary using this medication during lactation it should solve the issue of termination of breastfeeding. Category effects on the fetus by FDA - C.

Special instructions

Fludizol should be used with caution in patients with severe impaired liver or kidney diseases.

Therapy can be started before the results of seeding and other laboratory tests. However, an anti-infective therapy should be corrected accordingly when the results of these studies will be known.

Fludizol drug interactions

Simultaneous administration of Fludizol with:

  • coumarin anticoagulants marked increase in prothrombin time.
  • rifampicin observed shortening of the half-life of Fludizol. Fludizol Sorres Pharma increases the half-life of oral hypoglycemic agents - sulfonylureas in healthy people. Simultaneous use of Fludizol and oral hypoglycemic agents in diabetic patients is allowed, however, the physician should bear in mind the possibility of hypoglycemia.

    Fludizol in case of emergency / overdose

    Symptoms: nausea, vomiting, diarrhea and seizures in severe cases.

    Treatment: gastric lavage, forced diuresis, hemodialysis (three-hour dialysis reduces the plasma concentrations of approximately 50%), symptomatic therapy.

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    Fludizol pharmaceutical active ingredients containing related brand and generic drugs:


    Fludizol available forms, composition, doses:


    Fludizol destination | category:


    Fludizol Anatomical Therapeutic Chemical codes:


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    References

    1. Dailymed."FLUCONAZOLE TABLET [BRYANT RANCH PREPACK]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
    2. Dailymed."FLUCONAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
    3. "fluconazole". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

    Frequently asked Questions

    Can i drive or operate heavy machine after consuming Fludizol?

    Depending on the reaction of the Fludizol after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Fludizol not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

    Is Fludizol addictive or habit forming?

    Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

    Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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    Review

    sdrugs.com conducted a study on Fludizol, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Fludizol consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

    Visitor reports

    Visitor reported useful

    No survey data has been collected yet

    Visitor reported side effects

    No survey data has been collected yet

    Visitor reported price estimates

    No survey data has been collected yet

    Two visitors reported frequency of use

    How often in a day do you take the medicine?
    Are you taking the Fludizol drug as prescribed by the doctor?

    Few medications can be taken Once in a day more than prescribed when the doctor's advice mentions the medicine can be taken according to frequency or severity of symptoms. Most times, be very careful and clear about the number of times you are taking the medication. The report of sdrugs.com website users about the frequency of taking the drug Fludizol is mentioned below.
    Visitors%
    Once in a day2
    100.0%

    Four visitors reported doses

    What is the dose of Fludizol drug you are taking?
    According to the survey conducted among sdrugs.com website users, the maximum number of people are using the following dose 101-200mg. Few medications come in only one or two doses. Few are specific for adult dose and child dose. The dose of the medicine given to the patient depends on the severity of the symptom/disease. There can be dose adjustments made by the doctor, based on the progression of the disease. Follow-up is important.
    Visitors%
    101-200mg3
    75.0%
    201-500mg1
    25.0%

    One visitor reported time for results

    What is the time duration Fludizol drug must be taken for it to be effective or for it to reduce the symptoms?
    Most chronic conditions need at least some time so the dose and the drug action gets adjusted to the body to get the desired effect. The stastistics say sdrugs.com website users needed 5 days to notice the result from using Fludizol drug. The time needed to show improvement in health condition after using the medicine Fludizol need not be same for all the users. It varies based on other factors.
    Visitors%
    5 days1
    100.0%

    One visitor reported administration

    The drugs are administered in various routes, like oral or injection form. They are administered before food or after food. How are you taking Fludizol drug, before food or after food?
    Click here to find out how other users of our website are taking it. For any doubts or queries on how and when the medicine is administered, contact your health care provider immediately.
    Visitors%
    After food1
    100.0%

    Five visitors reported age

    Visitors%
    30-453
    60.0%
    46-601
    20.0%
    > 601
    20.0%

    Visitor reviews


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    The information was verified by Dr. Rachana Salvi, MD Pharmacology

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