Dolo-Menthoneurin

Heparin Sodium:

• Dolo-Menthoneurin (Heparin Sodium) reviews

Unfractionated Dolo-Menthoneurin (Heparin Sodium) (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight Dolo-Menthoneurin (Heparin Sodium) (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated Dolo-Menthoneurin (Heparin Sodium) is more specific than LMWH for thrombin. Furthermore, the effects of UH can typically be reversed by using protamine sulfate.

Indication: Unfractionated Dolo-Menthoneurin (Heparin Sodium) is indicated for prophylaxis and treatment of venous thrombosis and its extension, prevention of post-operative deep venous thrombosis and pulmonary embolism and prevention of clotting in arterial and cardiac surgery. In cardiology, it is used to prevent embolisms in patients with atrial fibrillation and as an adjunct antithrombin therapy in patients with unstable angina and/or non-Q wave myocardial infarctions (i.e. non-ST elevated acute coronary artery syndrome) who are on platelet glycoprotein (IIb/IIIa) receptor inhibitors. Additionally, it is used to prevent clotting during dialysis and surgical procedures, maintain the patency of intravenous injection devices and prevent in vitro coagulation of blood transfusions and in blood samples drawn for laboratory values.

Unfractionated Dolo-Menthoneurin (Heparin Sodium) is a highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from 3000 to 30,000 daltons. Dolo-Menthoneurin (Heparin Sodium) is obtained from liver, lung, mast cells, and other cells of vertebrates. Dolo-Menthoneurin (Heparin Sodium) is a well-known and commonly used anticoagulant which has antithrombotic properties. Dolo-Menthoneurin (Heparin Sodium) inhibits reactions that lead to the clotting of blood and the formation of fibrin clots both in vitro and in vivo. Small amounts of Dolo-Menthoneurin (Heparin Sodium) in combination with antithrombin III, a Dolo-Menthoneurin (Heparin Sodium) cofactor,) can inhibit thrombosis by inactivating Factor Xa and thrombin. Once active thrombosis has developed, larger amounts of Dolo-Menthoneurin (Heparin Sodium) can inhibit further coagulation by inactivating thrombin and preventing the conversion of fibrinogen to fibrin. Dolo-Menthoneurin (Heparin Sodium) also prevents the formation of a stable fibrin clot by inhibiting the activation of the fibrin stabilizing factor. Dolo-Menthoneurin (Heparin Sodium) prolongs several coagulation tests. Of all the coagulation tests, activated partial prothrombin time (aPTT) is the most clinically important value.

Menthol:

• Dolo-Menthoneurin (Menthol) reviews

Dolo-Menthoneurin (Menthol) is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. It is a waxy, crystalline substance, clear or white in color, which is solid at room temperature and melts slightly above. The main form of Dolo-Menthoneurin (Menthol) occurring in nature is (-)-menthol, which is assigned the (1R,2S,5R) configuration. Dolo-Menthoneurin (Menthol) has local anesthetic and counterirritant qualities, and it is widely used to relieve minor throat irritation.

Indication: Used to treat occasional minor irritation, pain, sore mouth, and sore throat as well as cough associated with a cold or inhaled irritants.

Dolo-Menthoneurin (Menthol) is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Menthol's ability to chemically trigger cold-sensitive receptors in the skin is responsible for the well known cooling sensation that it provokes when inhalated, eaten, or applied to the skin. It should be noted that Dolo-Menthoneurin (Menthol) does not cause an actual drop in temperature.