DRUGS & SUPPLEMENTS

Chinofen

Name: Chinofen drug & pharmaceuticals. Chinofen available forms, doses, prices
Creator: sdrugs.com
Published: 2021-11-11T10:10:10+00:00

How often in a day do you take medicine? How many times?

Chinofen uses

Pharmacological action
Pharmacokinetics
Why is Chinofen prescribed?
Dosage and administration
Chinofen side effects, adverse reactions
Contraindications
Special instructions
Chinofen drug interactions
Chinofen in case of emergency / overdose
Chinofen reviews

Pharmacological action

Chinofen is a centrally acting muscle relaxant; GABA_B-receptor agonist. It depresses mono-and polysynaptic reflexes presumably by reducing the release of excitatory amino acids from the terminals which occurs as a result of stimulation of presynaptic GABA-receptors. This medication does not affect the transmission of impulses in the nerve-muscle synapses; reduces skeletal muscle tone; has a moderate analgesic effect.

Pharmacokinetics

When Chinofen administered orally Chinofen is rapidly and completely absorbed from the gastrointestinal tract. C_max plasma levels achieved in 2-3 hours after administration. Plasma protein binding is about 30%. Chinofen crosses the placental barrier, excreted in breast milk; metabolized in the liver; excreted in the urine, mainly unchanged.

Why is Chinofen prescribed?

skeletal muscle spasticity in multiple sclerosis

spastic conditions of the spinal cord in diseases of infectious, degenerative, traumatic genesis

children cerebral palsy

Dosage and administration

For oral administration of Chinofen for adults at the beginning of treatment - 5 mg 3 times / day. For each 4-day treatment dose increased to 5 mg 3 times / day to the development of optimal therapeutic effect. Average daily dose is 30-75 mg, if necessary may increase up to 100-120 mg. The final daily dose is set individually so that together with the weakening of clonus and muscle spasms persisted muscle tone, which is sufficient for the implementation of active movements.

For patients with increased sensitivity to pharmaceutical drugs initial daily dose of Chinofen may be 5-10 mg, followed by a slower increase. For patients with renal insufficiency and during hemodialysis daily dose is 5 mg.

For children under 10 years daily dose is 0.75-2 mg / kg, over 10 years - 2.5 mg / kg. Treatment starts with a dose of 2.5 mg 4 times / day. Daily dose as for adults choose individually, increasing it every 3 days, in accordance with the clinical course of disease. Maintenance dose for children aged 1-2 years is 10-20 mg / day; for children aged 2-10 years - 30-60 mg / day.

Chinofen side effects, adverse reactions

CNS and peripheral nervous system: drowsiness, dizziness ; sometimes - apathy, fatigue, sleep disturbances, confusion; rarely - euphoria, depression, paresthesia, myalgia, muscle weakness, ataxia, tremor, nystagmus, accommodation disturbances, hallucinations; may be more frequent seizures and lowering the threshold of their appearance.

Digestive system: nausea, sometimes there are dry mouth, constipation, diarrhea, and in some cases - liver function abnormalities.

Cardiovascular system: sometimes - hypotension, deterioration of the cardiovascular system.

Other: sometimes - respiratory depression, rarely - dysuria, enuresis.

Side effects occur mainly at the beginning of treatment, with the rapid increase in dose, when administered a dose of 60 mg / day, as well as in elderly patients.

Contraindications

During pregnancy (especially in I trimester) Chinofen can be used only for health reasons.

Special instructions

Selection of individual daily dose of Chinofen recommended in the hospital.

Side effects are often transient, may disappear or decrease at lower doses of Chinofen Sanis Health. The need to interrupt therapy is rare. Side effects of Chinofen should be distinguished from symptoms of the disease which are treated. A cancellation of Chinofen should be conducted gradually, reducing the dose for 1-2 weeks.

With careful use in cerebrovascular disorders, psychotic states, schizophrenia, stomach ulcers and duodenal ulcers, respiratory failure, violations of liver and kidney, as well as in elderly patients. If concomitant treatment of epilepsy should be under strict medical supervision and without interruption of adequate therapy by anticonvulsant drugs. Patients with dysuria after Chinofen treatment can be observed hypertonicity of sphincter of the bladder and urine retention.

In patients with liver disease and diabetes should periodically monitor the level of hepatic transaminases, alkaline phosphatase and blood sugar.

During the treatment should refrain from potentially hazardous activities requiring increased attention and rapid psychomotor reactions.

Chinofen drug interactions

With the simultaneous application of Chinofen increases the effects of antihypertensive drugs, ethanol.

In an application of Chinofen with tricyclic antidepressants can significantly decrease muscle tone.

There is a described case of toxic reactions caused by the action of Chinofen (disturbance of consciousness, confusion, bradycardia, impaired visual acuity, hypotension, hypothermia) while using with ibuprofen in elderly patients with impaired renal function.

In an application with lithium therapy may be severe manifestations of hyperkinetic symptoms.

Patients suffering from Parkinson's disease while the application of Chinofen with levodopa and carbidopa may have hallucinations, confusion, agitation.

Chinofen in case of emergency / overdose

Symptoms: vomiting, muscular hypotonia, drowsiness, impaired accommodation of the eye, coma, respiratory depression, convulsions.

Treatment: induction of vomiting or gastric lavage, taking activated charcoal, symptomatic and supportive therapy (mechanical ventilation, maintenance of cardiovascular activity). There is no specific antidote.

Chinofen pharmaceutical active ingredients containing related brand and generic drugs:

Baclofen

Chinofen available forms, composition, doses:

Tablets; Oral; Baclofen 10 mg

Chinofen destination | category:

Human:
Skeletal muscle relaxants

Chinofen Anatomical Therapeutic Chemical codes:

M03BX01 - Baclofen

Chinofen pharmaceutical companies:

Chandra Bhagat Pharma

References

Dailymed."BACLOFEN TABLET [LAKE ERIE MEDICAL & SURGICAL SUPPLY DBA QUALITY CARE PRODUCTS LLC]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
Dailymed."BACLOFEN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
"baclofen". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Chinofen?

Depending on the reaction of the Chinofen after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Chinofen not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Chinofen addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

Review

sdrugs.com conducted a study on Chinofen, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Chinofen consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.