DRUGS & SUPPLEMENTS

Active ingredient: Clofazimine

Name: Clofazimine drugs and health products
Creator: sdrugs.com
Published: 2021-11-11T10:10:10+00:00

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Clofazimine uses

Clofazimine reviews

A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)

Indication: For the treatment of lepromatous leprosy, including dapsone-resistant lepromatous leprosy and lepromatous leprosy complicated by erythema nodosum leprosum.

Clofazimine exerts a slow bactericidal effect on Mycobacterium leprae (Hansen's bacillus). Clofazimine inhibits mycobacterial growth and binds preferentially to mycobacterial DNA. Clofazimine also exerts antiinflammatory properties in controlling erythema nodosum leprosum reactions. Clofazimine is highly lipophilic and tends to be deposited predominantly in fatty tissue and in cells of the reticuloendothelial system. It is taken up by macrophages throughout the body. Measurement of the minimum inhibitory concentration (MIC) of Clofazimine against leprosy bacilli in vitro is not yet feasible. In the mouse footpad system, the multiplication of M.leprae is inhibited by introducing 0.0001%- 0.001% Clofazimine in the diet. Although bacterial killing may begin shortly after starting the drug, it cannot be measured in biopsy tissues taken from patients for mouse footpad studies until approximately 50 days after the start of therapy.

Clofazimine available forms, composition, doses:

	Price
Clofazimine powder	187.2 USD

Indications and Usages:

ATC codes:

J04BA01

ICD-10 codes:

Clofazimine destination | category:

Human:
Antileprotics

Drugs with same active ingredients (Pharmaceutical companies):

Clofazimine
Clofozine (AstraZeneca)
Hansepran (Sarabhai Piramal Pharma)
Lamcoin (Pond's Chemical Thailand)
Lampren (Novartis)
Lamprene (Alliance Pharmaceuticals)
Lamprene (Almus)
Lamprene (Institute of Pharmaceutical Research and Technology)
Lamprene (Novartis)
Neozimina (Neo Quimica Comercio e Industria Laboratorio)

References

"clofazimine". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
"clofazimine". http://www.drugbank.ca/drugs/DB0084... (accessed August 28, 2018).
"D959AE5USF: The UNique Ingredient Identifier (UNII) is an alphanumeric substance identifier from the joint FDA/USP Substance Registration System (SRS).". https://www.fda.gov/ForIndustry/Dat... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Clofazimine?

Depending on the reaction of the Clofazimine after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Clofazimine not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Clofazimine addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

Review

sdrugs.com conducted a study on Clofazimine, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Clofazimine consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.