Pharma company: sintez
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List of sintez products:
- Acecardol - Pharmacological action Acecardol is a NSAIDs. It has anti-inflammatory, analgesic and antipyretic effect, and inhibits platelet aggregation. The mechanism of action is associated with inhibition of COX activity - the main enzyme metabolism of arachidonic acid which is a precursor of prostaglandins which play a major role in the pathogenesis of inflammation, pain and fever. Reduction of prostaglandins (mainly E1) in the thermoregulation center leads to a decrease in body temperature due to...
- Aciclovir-Akos - Pharmacological action Aciclovir-Akos is an antiviral agent. Thymidine kinase of virus-infected cells actively converts acyclovir through a series of sequential reactions in the mono-, di- and triphosphate of acyclovir. The latter interacts with the viral DNA polymerase, and embedded in DNA, which is synthesized for new viruses. Thus it is formed a "defective" viral DNA which leads to suppression of replication of new generations of viruses. This mediciine acyclovir is active against...
- Amikacin - Amikacin is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A. Similar to other aminoglycosides, amikacin disrupts bacterial protein synthesis by binding to the 30S ribosome of susceptible organisms. Binding interferes with mRNA binding and tRNA acceptor sites leading to the production of non-functional or toxic peptides. Other mechanisms not fully understood may confer the bactericidal effects of amikacin. Amikacin is also nephrotoxic and ototoxic. Indication: For short-term...
- Amitriptyline - Pharmacological action Amitriptyline is an antidepressant tricyclic group of compounds derived dibenzocycloheptadiene. The mechanism of antidepressant action is associated with an increased concentration of norepinephrine in the synapses and / or serotonin in the central nervous system depression due to reverse neuronal capture of these mediators. When anxiety and depressive states this medication reduces anxiety, agitation and depressive symptoms. Also this drug has some analgesic...
- Amlorus
- Amosin
- Amphoglucamin
- Amphotericin B - BOXED WARNING This drug should be used primarily for treatment of patients with progressive and potentially life-threatening fungal infections; it should not be used to treat noninvasive forms of fungal disease such as oral thrush, vaginal candidiasis and esophageal candidiasis in patients with normal neutrophil counts. Amphotericin B for Injection should no be given in doses greater than 1.5 mg/kg. ...
- Ampicillin - DESCRIPTION: Ampicillin for injectable suspension, veterinary is a broad-spectrum penicillin which has bactericidal activity against a wide range of common gram-positive and gram-negative bacteria. Each 25 g vial contains: 25 g ampicillin activity as ampicillin trihydrate, 90 mg methylparaben (as preservative), 10 mg propylparaben (as preservative), 200 mg lecithin, 500 mg povidone, 200 mg sodium chloride, 600 mg sodium...
- Anaprilin - Pharmacological action Propranolol is a non-selective beta-blocker. This medication has antihypertensive, antianginal and antiarrhythmic action. The hypotensive effect is associated with a decrease in minute volume of blood, sympathetic stimulation of peripheral vascular disease, decreased activity of the renin-angiotensin system (has a value in patients with initial hypersecretion of renin), sensitivity of baroreceptors of the aortic arch (not going to enhance their activity in response...
- Arlet
- Atenolol - Pharmacological action Atenolol is a cardioselective beta1-blocker without intrinsic sympathomimetic activity. This medication has antihypertensive, antianginal and antiarrhythmic action. Atenolol reduces the stimulatory effect on the heart sympathetic innervation and circulating catecholamines. The hypotensive effect of this drug is associated with a decrease in minute volume of blood, decreased activity of the renin-angiotensin system (has a greater significance for patients with...
- Azithrus
- Azithrus Forte
- Baby Powder
- Benzylpenicillin
- Bicillin-3
- Bicillin-5
- Bifosin
- Calcium Chloride - SPL UNCLASSIFIED SECTION 1 Gram (100 mg/mL) Represents 27 mg (1.4 mEq) Ca ++ /mL Ansyr™ Plastic Syringe A...
- Captopril - SPL UNCLASSIFIED SECTION CAPTOPRIL TABLETS, USP Rev. 03/16 Rx Only WARNING: FETAL TOXICITY • When pregnancy is detected, discontinue captopril tablets as soon as possible. • Drugs...
- Carbamazepine - WARNINGS SERIOUS DERMATOLOGIC REACTIONS AND HLA-B * 1502 ALLELE SERIOUS AND SOMETIMES FATAL DERMATOLOGIC REACTIONS, INCLUDING TOXIC EPIDERMAL NECROLYSIS (TEN) AND STEVENS-JOHNSON SYNDROME (SJS), HAVE BEEN REPORTED DURING TREATMENT WITH CARBAMAZEPINE. THESE REACTIONS ARE ESTIMATED TO OCCUR IN 1 TO 6 PER 10,000 NEW USERS IN COUNTRIES WITH MAINLY CAUCASIAN POPULATIONS, BUT THE RISK IN SOME ASIAN COUNTRIES IS ESTIMATED TO BE ABOUT 10 TIMES...
- Cefalexin
- Cefalotin - A cephalosporin antibiotic. [PubChem] Indication: Used to prevent infection during surgery and to treat many kinds of infections of the blood, bone or joints, respiratory tract, skin, and urinary tract. Cefalotin (INN) or cephalothin (USAN) is a semisynthetic first generation cephalosporin having a broad spectrum of antibiotic activity that is administered parenterally.
- Cefat
- Cefazolin - SPL UNCLASSIFIED SECTION To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefazolin for Injection and other antibacterial drugs, Cefazolin for Injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DESCRIPTION Cefazolin for Injection, USP is a semi-synthetic cephalosporin for parenteral...
- Cefoperus
- Cefosin
- Ceftazidim
- Ceftriaxon
- Cefurus
- Ciprofloxacin - Chemical Structure WARNING Fluoroquinolones, including Ciprofloxacin Tablets, are associated with an increased risk of tendinitis and tendon rupture in all ages. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants (See WARNINGS ). ...
- Clarithrosin
- Clotrimazole - Pharmacological action Clotrimazole is an antifungal agent of imidazole derivatives group for topical use. This medication has an effect at the expense of the synthesis of ergosterol, which is part of the cell membrane of fungi. Clotrimazole has a broad spectrum of action. Clotrimazole is active against dermatophytes, molds, fungi of the genus Candida, Malassezia furfur. This drug is also active against Corynebacterium minutissimum, Streptococcus spp., Staphylococcus spp., Trichomonas...
- Combitropil
- Corvalol
- Crataegi Tinctura
- Defislez
- Diclofenac - Pharmacological action NSAIDs, a derivative of phenylacetic acid, diclofenac has a pronounced anti-inflammatory, analgesic and mild antipyretic effect. The mechanism of action is associated with inhibition of COX activity - the main enzyme metabolism of arachidonic acid, which is a precursor of prostaglandins, which play a major role in the pathogenesis of inflammation, pain and fever. Analgesic effect is due to two mechanisms: peripheral (indirectly, through suppression of prostaglandin...
- Doxycycline - Pharmacological action Doxycycline is an semisynthetic tetracycline group's antibiotic of broad-spectrum. This medication has bacteriostatic action due to suppression of protein synthesis of pathogens. It active against aerobic gram-positive bacteria: Staphylococcus spp. (including strains producing penicillinase), Streptococcus spp. (including Streptococcus pneumoniae), Bacillus anthracis, Listeria monocytogenes; anaerobic bacteria: Clostridium spp. Doxycycline is also active against...
- Drotaverine - Drotaverine (INN, also known as drotaverin) is an antispasmodic drug, structurally related to papaverine. Drotaverine is a selective inhibitor of phosphodiesterase 4, and has no anticholinergic effects. Drotaverine has been shown to possess dose-dependant analgesic effects in animal models. One small study has shown drotaverine to be eliminated mainly non-renally. Indication: Used in the treatment of functional bowel disorders and alleviating pain in renal colic. Drotaverine is a spasmolytic...
- Enalapril - Enalapril information Enalapril is one of the most effective anti-hypertensive drugs in the market. Belonging to the angiotensin-converting-enzyme inhibitors (ACE inhibitors) category of drugs, Enalapril helps to keep raising blood pressure under control thereby reducing the risk factors of this disease. Since hypertension works out the heart muscles to cause early arterial failure, Enalapril stands in the way and helps to keep your heart healthy, indirectly. Like all other ACE inhibitors,...
- Erythromycin - SPL UNCLASSIFIED SECTION Film-coated Tablets Rx only To reduce the development of drug-resistant bacteria and maintain the effectiveness of Erythromycin Tablets and other antibacterial drugs, Erythromycin Tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DESCRIPTION ...
- Erythromycin Phosphate
- Ethambusin
- Ethanol - Active Ingredients Ethyl Alcohol 80% Purpose Antiseptic Uses For handwashing to decrease bacteria on the skin recommended for repeated use ...
- Euphylline
- Famotidin
- Gentamicin - Gentamicin Sulfate Solution 100 mg/mL Gentamicin Sterile Multiple Dose Vial For Use in Horses Only For intra-uterine use in horses only. CAUTION : Federal law restricts this drug to use by or on the order of a licensed veterinarian. ...
- Gliclazide - Gliclazide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic...
- Glucose
- Halmanin
- Heparin - Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of...
- Hydrocortisone - Active Ingredients: Hydrocortisone Acetate 0.50% Purpose Anti-itch Uses: to soothe: • skin irritations • itching • dermatitis • eczema • flea bites. Warnings For external use only on adult dogs. ...
- Ibuprofen - SPL UNCLASSIFIED SECTION Rx Only Cardiovascular Risk • NSAIDs may cause an increased risk of serious cardiovascular thrombotic events,...
- Isoniazid - SPL UNCLASSIFIED SECTION Rev. 02/11 Rx Only WARNING Severe and sometimes fatal hepatitis associated with isoniazid therapy has been reported and may occur or may develop even after many months of treatment. The risk of developing hepatitis is age related. Approximate case rates by age are: less than 1 per 1,000 for persons under 20 years of age, 3 per 1...
- Kanamycin - SPL UNCLASSIFIED SECTION To reduce the development of drug-resistant bacteria and maintain the effectiveness of Kanamycin Injection, USP and other antibacterial drugs, Kanamycin Injection, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. BOXED WARNING Patients treated with aminoglycosides by any route should be under close...
- Ketorolac - A pyrrolizine carboxylic acid derivative structurally related to indomethacin. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed) Indication: For the short-term (~5 days) management of moderately severe acute pain that requires analgesia at the opioid level, usually in a postoperative setting. Ketorolac, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain....
- Lavenum
- Leflobact
- Levomycetin
- Lidocaine - Pharmacological action Lidocaine is an antiarrhythmic agent of class IB, local anesthetic, a derivative of acetanilide. This medication has membrane stabilizing activity. Lidocaine causes a blockade of sodium channels of excitable membranes of neurons and the membrane of cardiomyocytes. This drug reduces the duration of the action potential and effective refractory period in Purkinje fibers, inhibits their automaticity. In this case, lidocaine inhibits electrical activity in depolarized,...
- Lincomycin - LincoMed® 300 lincomycin injection, USP Swine Antibiotic Restricted Drug (California) - Use only as Directed. For Use in Animals Only ANADA 200-368,...
- Lofox
- Menovasin
- Metronidazole - Pharmacological action Metronidazole is an anti protozoal agent. It is believed that the mechanism of action is associated with DNA damage-sensitive microorganisms. Active against Trichomonas vaginalis, Gardnerella vaginalis, Giardia lamblia, Entamoeba histolytica, and obligate anaerobic bacteria (including Bacteroides spp., Fusobacterium spp.). Aerobic bacteria are resistant to metronidazole. In combination with amoxicillin Metronidazole is active against Helicobacter pylori. It is...
- Movasin
- Mycoket
- Naphthyzin
- Neohaemodes
- Neohemodez
- Nesopin
- Nicergoline - An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease. [PubChem] Indication: For the treatment of senile dementia, migraines of vascular origin, transient ischemia, platelet hyper-aggregability, and macular degeneration. Nicergoline is a potent vasodilator (improves brain blood flow). On the cerebral level it prompts a lowering of vascular resistance, an increase in...
- Nitroxoline - Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections. It is a fluorquinolone that is active against bacterial gyrases. Indication: Nitroxoline is an antibiotic agent.
- Ofloxacin - Pharmacological action Ofloxacin is an antimicrobial agents of broad-spectrum action type from fluoroquinolone group. Bactericidal action of ofloxacin is due to blockage of the enzyme DNA gyrase in bacterial cells. This medication is highly active against most of gram-negative bacteria: Escherichia coli, Salmonella spp., Shigella spp., Proteus spp., Morganella morganii, Klebsiella spp. (including Klebsiella pneumoniae), Enterobacter spp., Serratia spp., Citrobacter spp., Yersinia spp.,...
- Omeprazole - WARNINGS AND PRECAUTIONS Bone Fracture ( 5.3 ) 09/2010 WARNINGS AND PRECAUTIONS Diminished anti-platelet activity of clopidogrel ( 5.4 ) 01/2011 ...
- Oxacillin - SPL UNCLASSIFIED SECTION For Intramuscular or Intravenous Injection To reduce the development of drug-resistant bacteria and maintain the effectiveness of Oxacillin for Injection and other antibacterial drugs, Oxacillin for Injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DESCRIPTION ...
- Oxamp
- Oxamp-Sodium
- Paracetamol - Pharmacological action Paracetamol is an analgesic-antipyretic. It has analgesic, antipyretic and weak anti-inflammatory action. The mechanism of action is associated with inhibition of prostaglandin synthesis, the predominant influence on the thermoregulation center in the hypothalamus, enhances heat transfer. Why is Paracetamol prescribed? Pain weak and moderate intensity of different genesis (including headache, migraine, toothache, neuralgia, myalgia, algomenorrhea; pain in trauma,...
- Pefloxacin - A synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria. [PubChem] Indication: For the treatment of uncomplicated gonococcal urethritis in males and for gram-negative-bacterial infections in the gastrointestinal system and the genitourinary tract. Pefloxacin is a fluoroquinolone antibiotic. Flouroquinolones such as pefloxacin possess excellent activity against gram-negative aerobic bacteria such as E.coli and Neisseria...
- Pilocarpine - A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma. [PubChem] Indication: For the treatment of radiation-induced dry mouth (xerostomia) and symptoms of dry mouth in patients with Sjögrens syndrome. Pilocarpine is a choline ester miotic and a positively charged quaternary ammonium compound. Pilocarpine, in appropriate dosage, can increase secretion by the exocrine glands. The sweat, salivary, lacrimal, gastric,...
- Pilotimol
- Pilotimol Mini
- Piperazine - PACKAGE CONTENTS: Blister of 12 capsules ACTIVE INGREDIENT: Each capsule contains 140 mg Piperazine (as Citrate) PURPOSE: For the removal of large roundworms, Toxocara canis and Toxacaris leonina , in...
- Piracetam
- Polynadim
- Prednisolone - SPL UNCLASSIFIED SECTION For Oral Use in Dogs Only CAUTION Federal law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION Prednisolone, like methylprednisolone, is a potent anti-inflammatory steroid. Prednisolone, 11,17,21-trihydroxypregna-1,4-diene-3,20-dione, is a synthetic dehydrogenated...
- Prostudox
- Ranitidine - Pharmacological action Ranitidine is a blocker of histamine H2-receptors. Inhibits basal and stimulated by histamine, gastrin and acetylcholine (to a lesser extent) the secretion of hydrochloric acid. Increases the pH of gastric contents and reduces the activity of pepsin. The duration of action of ranitidine with a single admission - 12 hours. Pharmacokinetics After oral administration, ranitidine is rapidly absorbed from the gastrointestinal tract. Eating and antacids significantly...
- Rhinorus
- Rifampicin
- Rizosin - Pharmacological action Ions of sodium and chlorine are the major inorganic components of the extracellular fluid, maintaining an appropriate osmotic pressure of blood plasma and extracellular fluid. Isotonic solution of Sodium Chloride fills a deficit of body fluids during dehydration. Hypertonic solution of sodium chloride for IV injection provides a correction of osmotic pressure of extracellular fluid and blood plasma. When applied topically in ophthalmology sodium chloride has...
- Salicylic Acid - Pharmacological action Salicylic Acid is pharmaceytical active ingredient for topical use. Inhibits the secretion of the sebaceous and sweat glands. At low concentrations it has keratoplastic and in high doses keratolytic effect. Salicylic acid has a weak antimicrobial activity. Why is Salicylic Acid prescribed? Monotherapy with salicylic acid and as part of combination therapies for inflammatory, infectious and other skin lesions, including burns, psoriasis, eczema, dyskeratosis,...
- Salicylic-Zinc Pasta
- Sodium Chloride - Pharmacological action Ions of sodium and chlorine are the major inorganic components of the extracellular fluid, maintaining an appropriate osmotic pressure of blood plasma and extracellular fluid. Isotonic solution of Sodium Chloride fills a deficit of body fluids during dehydration. Hypertonic solution of sodium chloride for IV injection provides a correction of osmotic pressure of extracellular fluid and blood plasma. When applied topically in ophthalmology sodium chloride has...
- Spironolactone - SPL UNCLASSIFIED SECTION Rx only WARNING Spironolactone has been shown to be a tumorigen in chronic toxicity studies in rats (see Precautions ). Spironolactone should be used only in those conditions described under Indications and Usage ...
- Streptomycin - SPL UNCLASSIFIED SECTION SPL UNCLASSIFIED To reduce the development of drug-resistant bacteria and maintain the effectiveness of streptomycin and other antibacterial drugs, streptomycin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. WARNING THE RISK OF SEVERE NEUROTOXIC REACTIONS IS SHARPLY INCREASED IN...
- Sulfacyl
- Sulfacyl Sodium
- Sultasin
- Sultasyn
- Suxamethonium
- Tetracycline - Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane causing intracellular components to leak from bacterial cells. Indication: Used to treat...
- Thiopental - A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not produce any excitation but has poor analgesic and muscle relaxant properties. Small doses have been shown to be anti-analgesic and lower the pain threshold. (From Martindale,...
- Timolol - DESCRIPTION Betimol ® (timolol ophthalmic solution), 0.25% and 0.5%, is a non-selective beta-adrenergic antagonist for ophthalmic use. The chemical name of the active ingredient is (S)-1-[(1,1-dimethylethyl)amino]-3-[(4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol. Timolol hemihydrate is the levo isomer. Specific rotation is [α] 25 405nm =-16° (C=10% as the hemihydrate form in 1N HCl). The molecular...
- Valsaforce
- Vancorus
- Vedicardol - Carvedilol information Carvedilol is a blood pressure medication and belongs to the class of drugs known as beta-blockers. These beta-blockers affect the circulatory system, which includes the human heart, arteries and veins. Carvedilol indications This medication is used primarily in treating hypertension or high blood pressure. Carvedilol warnings Taking Carvedilol may not be advisable if you have any of the following conditions: asthma heart problems such as low blood pressure...
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The information was verified by Dr. Rachana Salvi, MD Pharmacology
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