Rhoxal-Atenolol - Pharmacological action Atenolol is a cardioselective beta1-blocker without intrinsic sympathomimetic activity. This medication has antihypertensive, antianginal and antiarrhythmic action. Atenolol reduces the stimulatory effect on the heart sympathetic innervation and circulating catecholamines. The hypotensive effect of this drug is associated with a decrease in minute volume of blood, decreased activity of the renin-angiotensin system (has a greater significance for patients with...
Rhoxal-Simvastatin - Pharmacological action Simvastatin is a hypolipidemic agent from a group of statins, an inhibitor of HMG-CoA reductase. This medication is a prodrug because it has in its structure the closed lactone ring which is hydrolyzed after intake. Lipid-lowering effect of statins is associated with lower levels of total cholesterol by LDL-C. Reducing cholesterol is dose-dependent and is not linear but exponential. Statins do not affect the activity of lipoprotein and hepatic lipase, have no...
Rhoxal-Zopiclone - Pharmacological action Zopiclone is a sleeping drug from group of cyclopyrrolone derivatives. This drug is "non benzodiazepine" agonist of benzodiazepine receptors. Zopiclone also has sedative, anxiolytic, muscle-relaxing center, anticonvulsant and amnesic properties. Like a derivative of benzodiazepine zopiclone enhances GABA-ergic processes in the brain, interacting with the benzodiazepine receptors, as a result of the increased sensitivity of GABA-receptors to the neurotransmitter....
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