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DRUGS & SUPPLEMENTS
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Zonix
What is the dose of the medication you are taking? |
Zonix uses
Pharmacological action
Zonix is a sleeping drug from group of cyclopyrrolone derivatives. This drug is "non benzodiazepine" agonist of benzodiazepine receptors. Zonix also has sedative, anxiolytic, muscle-relaxing center, anticonvulsant and amnesic properties. Like a derivative of benzodiazepine Zonix enhances GABA-ergic processes in the brain, interacting with the benzodiazepine receptors, as a result of the increased sensitivity of GABA-receptors to the neurotransmitter. However, Zonix apparently interacts with other parts of the benzodiazepine receptor than benzodiazepines.
Zonix reduced sleep time, reduces the number of nighttime awakenings, increases total sleep time. This medication almost has no effect on sleep structure, does not reduce significantly the amount of REM sleep. Consequences of the phenomenon of waking up are missing or expressed little. Readmission Zonix are not accompanied by cumulation.
Pharmacokinetics
Zonix rapidly and completely absorbed from the gastrointestinal tract. Cmax achieved within 1-3 hours. Zonix easily passes through gistogematicheskie barriers including the BBB and it is distributed in organs and tissues including brain. T1/2 is 5.5-6 hours, not accumulates.
Why is Zonix prescribed?
Sleep disturbance, transient, situational or chronic insomnia; sleep disturbances in mental disorders, bronchial asthma with nocturnal seizures (in combination with single dose daily dose of theophylline).
Dosage and administration
The average therapeutic dose of Zonix is 7.5 mg orally at night, in cases of severe insomnia the dose can be increased up to 15 mg. In elderly patients, as well as abnormal liver function is used 3.75 mg.
Zonix side effects, adverse reactions
Digestive system: a feeling of bitter or metallic taste in the mouth, dry mouth, nausea, and vomiting.
CNS: dizziness, headache, drowsiness, confusion, anterograde amnesia, hallucinations, nightmares.
Dermatologic reactions: skin rash.
Zonix contraindications
Severe respiratory failure, pregnancy, lactation, children and teens under 15 years old, hypersensitivity to Zonix.
Using during pregnancy and breastfeeding
Zonix is contraindicated during pregnancy (especially in I and III trimester) and lactation (breastfeeding). If a woman uses Zonix in III trimester of pregnancy there are possible violations of the nervous system in the newborn, the emergence of withdrawal syndrome. If the woman is prescribed by a doctor took Zonix immediately prior to labor and delivery, it needs a constant medical surveillance for the newborn. At the time of treatment it should be stoped breastfeeding (zopiclone penetrates into breast milk).
Special instructions
With caution use in patients with severe liver failure.
Risk of drug dependence is minimal if the duration of Zonix did not exceed 4 weeks. However, the potential danger of Zonix dependence to exist.
During the period of treatment patients should to exclude the use of alcohol.
On the next day after taking the drug it should be cautious to drive and operate machinery.
Zonix drug interactions
Simultaneous administration of Zonix with trimipramine reduces the concentration of trimipramine in plasma and its effect.
Zonix increases the influence of CNS depressants.
Zonix in case of emergency / overdose
Symptoms: CNS depression of varying severity (from drowsiness to loss of consciousness).
Treatment: gastric lavage, taking activated charcoal, if necessary - symptomatic therapy. As a specific antidote used benzodiazepine receptor antagonist flumazenil (in hospital). Hemodialysis is ineffective.
Zonix pharmaceutical active ingredients containing related brand and generic drugs:
Zonix available forms, composition, doses:
Zonix destination | category:
Zonix Anatomical Therapeutic Chemical codes:
Zonix pharmaceutical companies:
References
- "zopiclone". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
- "zopiclone". http://www.drugbank.ca/drugs/DB0119... (accessed August 28, 2018).
- "zopiclone: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/... (accessed August 28, 2018).
Frequently asked Questions
Can i drive or operate heavy machine after consuming Zonix?Depending on the reaction of the Zonix after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Zonix not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.
Is Zonix addictive or habit forming?Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
Review
sdrugs.com conducted a study on Zonix, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Zonix consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.Visitor reports
One visitor reported useful
How is the drug Zonix useful in reducing or relieving the symptoms? How useful is it?According to the survey conducted by the website sdrugs.com, there are variable results and below are the percentages of the users that say the medicine is useful to them and that say it is not helping them much. It is not ideal to continue taking the medication if you feel it is not helping you much. Contact your healthcare provider to check if there is a need to change the medicine or if there is a need to re-evaluate your condition. The usefulness of the medicine may vary from patient to patient, depending on the other diseases he is suffering from and slightly depends on the brand name.
| Visitors | % | ||
|---|---|---|---|
| Useful | 1 | 100.0% | |
Visitor reported side effects
No survey data has been collected yetVisitor reported price estimates
No survey data has been collected yetVisitor reported frequency of use
No survey data has been collected yetTwo visitors reported doses
What is the dose of Zonix drug you are taking?According to the survey conducted among sdrugs.com website users, the maximum number of people are using the following dose 6-10mg. Few medications come in only one or two doses. Few are specific for adult dose and child dose. The dose of the medicine given to the patient depends on the severity of the symptom/disease. There can be dose adjustments made by the doctor, based on the progression of the disease. Follow-up is important.
| Visitors | % | ||
|---|---|---|---|
| 6-10mg | 2 | 100.0% | |
Visitor reported time for results
No survey data has been collected yetVisitor reported administration
No survey data has been collected yetOne visitor reported age
| Visitors | % | ||
|---|---|---|---|
| 30-45 | 1 | 100.0% | |
Visitor reviews
There are no reviews yet. Be the first to write one! |
The information was verified by Dr. Rachana Salvi, MD Pharmacology