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DRUGS & SUPPLEMENTS
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Tramadol
How old is patient? |
Tramadol uses
Pharmacological action
Tramadol Karnataka Antibiotics & Pharmaceuticals is an opioid analgesic, a derivative of cyclohexanol. It is non-selective agonist of mu-, delta- and kappa-receptors in the CNS. Tramadol is a racemate and (-) of isomers (50% / 50%) which in various ways are involved in analgesic effects. The isomer (+) is a pure agonist opioid receptors, it has low tropism and has a pronounced selectivity for different subtypes of receptors. The isomer (-) inhibiting neuronal capture of noradrenaline activates the descending noradrenergic influence. Thats why it is broken transmission of pain impulses in the gelatinous substance of spinal cord.
Tramadol Karnataka Antibiotics & Pharmaceuticals causes sedation. At therapeutic doses this medication almost not get respiratory depression. Tramadol has also an antitussive effect.
Pharmacokinetics
After oral administration Tramadol Karnataka Antibiotics & Pharmaceuticals quickly and almost completely absorbed from the gastrointestinal tract (90%). Cmax in plasma obtained in 2 h after taking this medication. Bioavailability in single dose is 68% and increases with repeated use.
Plasma protein binding is 20%. Tramadol is widely distributed in tissues. Vd after oral administration and intravenous injection is 306 l and 203 l respectively. This drug crosses the placental barrier in a concentration equal to the concentration of the active substance in the plasma. 0.1% is excreted in breast milk.
Tramadol metabolised by demethylation and conjugation to 11 metabolites, of which only 1 is active.
This medicine excreted by the kidneys - 90% and through the intestines - 10%.
Why is Tramadol Karnataka Antibiotics & Pharmaceuticals prescribed?
Moderate and severe pain of various origins. Conducting painful diagnostic or therapeutic procedures.
Dosage and administration
A single oral dose for adults and children over 14 years is 50 mg, rectally - 100 mg, IV slowly or IM - 50-100 mg. If for parenteral injection efficiency is not enough, it is possible oral taking in a dose of 50 mg after 20-30 minutes.
For children aged 1 to 14 years set the dose rate of 1-2 mg / kg.
The duration of treatment is determined individually.
The maximum dose for adults and children over 14 years regardless of method of administration is 400 mg / day.
Tramadol Karnataka Antibiotics & Pharmaceuticals side effects, adverse reactions
CNS: dizziness, weakness, drowsiness, confusion, and in some cases - seizures and convulsions of cerebral origin.
Cardio-vascular system: tachycardia, orthostatic hypotension, collapse.
Digestive system: dry mouth, nausea, vomiting.
Metabolism: increased sweating.
Musculoskeletal system: miosis.
Tramadol Karnataka Antibiotics & Pharmaceuticals contraindications
Using during pregnancy and breastfeeding
During pregnancy patients should avoid prolonged use of Tramadol Karnataka Antibiotics & Pharmaceuticals because the risk of addiction in the fetus and the occurrence of withdrawal in the neonatal period.
If necessary using in lactation should be aware that Tramadol in small amounts excreted in breast milk. In the case of long-term treatment can not been excluded the possibility of drug dependence.
Tramadol Karnataka Antibiotics & Pharmaceuticals is not recommended for treatment of withdrawal syndrome drugs.
Patients need to avoid combination with MAO inhibitors.
During the period of treatment with Tramadol Karnataka Antibiotics & Pharmaceuticals you should avoid to take alcohol.
Tramadol in the form of long-acting formulations should not be used in children under the age of 14 years.
During the period of Tramadol using is not recommended to engage in activities that require special attention, speed of psychomotor reactions.
Special instructions
With caution Tramadol Karnataka Antibiotics & Pharmaceuticals should be used in convulsions of central genesis of drug dependence, confusion, patients with impaired renal function and liver, as well as increased sensitivity to other opioid receptor agonists.
Tramadol should not be used beyond the period justified from a therapeutic point of view.
Tramadol Karnataka Antibiotics & Pharmaceuticals drug interactions
Simultaneous administration of Tramadol Karnataka Antibiotics & Pharmaceuticals with:
Tramadol Karnataka Antibiotics & Pharmaceuticals in case of emergency / overdose
Symptoms: respiratory depression, until apnea, seizures, Pupillary, anuria, coma.
Treatment: IV injection of naloxone (a specific antagonist), gastric lavage, maintenance of vital functions.
Tramadol pharmaceutical active ingredients containing related brand and generic drugs:
Tramadol available forms, composition, doses:
| Price | |
| Capsules, Extended Release; Oral; Tramadol Hydrochloride 100 mg | |
| Capsules, Extended Release; Oral; Tramadol Hydrochloride 200 mg | |
| Capsules, Extended Release; Oral; Tramadol Hydrochloride 300 mg | |
| Capsules; Oral; Tramadol Hydrochloride | |
| Capsules; Oral; Tramadol Hydrochloride 100 mg | |
| Capsules; Oral; Tramadol Hydrochloride 50 mg | |
| Drops; Oral; Tramadol Hydrochloride | |
| Drops; Oral; Tramadol Hydrochloride 100 mg / ml | |
| Injectable; Injection; Tramadol Hydrochloride 100 mg / ml | |
| Injectable; Injection; Tramadol Hydrochloride 50 mg / ml | |
| Solution; Oral; Tramadol Hydrochloride | |
| Suppositories; Rectal; Tramadol Hydrochloride | |
| Suppositories; Rectal; Tramadol Hydrochloride 100 mg | |
| Tablets, Effervescent; Oral; Tramadol Hydrochloride 50 mg | |
| Tablets, Extended Release; Oral; Tramadol Hydrochloride 100 mg | |
| Tablets, Extended Release; Oral; Tramadol Hydrochloride 200 mg | |
| Tablets, Extended Release; Oral; Tramadol Hydrochloride 300 mg | |
| Tablets, Film-Coated; Oral; Tramadol Hydrochloride 50 mg | |
| Tablets, Orally Disintegrating; Oral; Tramadol Hydrochloride 50 mg | |
| Tablets, Retard; Oral; Tramadol Hydrochloride 100 mg | |
| Tablets, Retard; Oral; Tramadol Hydrochloride 150 mg | |
| Tablets, Retard; Oral; Tramadol Hydrochloride 200 mg | |
| Tablets; Oral; Tramadol Hydrochloride | |
| Tablets; Oral; Tramadol Hydrochloride 100 mg | |
| Tablets; Oral; Tramadol Hydrochloride 50 mg | |
| TraMADol HCl 100 mg 24 Hour tablet | 3.78 USD |
| TraMADol HCl 200 mg 24 Hour tablet | 6.25 USD |
| Tramadol hcl 50 mg tablet | 0.7 USD |
| Tramadol hcl powder | 29.08 USD |
| Tramadol-Acetaminophen 37.5-325 mg tablet | 1.07 USD |
| Ultram 50 mg tablet | 1.99 USD |
| Ultram ER 100 mg 24 Hour tablet | 4.62 USD |
| Ultram ER 200 mg 24 Hour tablet | 7.64 USD |
| Ultram ER 300 mg 24 Hour tablet | 10.66 USD |
| Ultram er 100 mg tablet | 4.44 USD |
| Ultram er 200 mg tablet | 7.35 USD |
| Ultram er 300 mg tablet | 10.25 USD |
Tramadol destination | category:
Tramadol Anatomical Therapeutic Chemical codes:
Tramadol pharmaceutical companies:
References
- Dailymed."TRAMADOL HYDROCHLORIDE TABLET [LAKE ERIE MEDICAL DBA QUALITY CARE PRODUCTS LLC]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
- "Tramadol". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
- "Tramadol". http://www.drugbank.ca/drugs/DB0019... (accessed August 28, 2018).
Frequently asked Questions
Can i drive or operate heavy machine after consuming Tramadol?Depending on the reaction of the Tramadol after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Tramadol not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.
Is Tramadol addictive or habit forming?Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
Review
sdrugs.com conducted a study on Tramadol, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Tramadol consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.Visitor reports
Visitor reported useful
No survey data has been collected yetVisitor reported side effects
No survey data has been collected yetOne visitor reported price estimates
What is your opinion about drug cost? Did you feel the cost is apt, or did you feel it is expensive?The report given by the sdrugs.com website users shows the following figures about several people who felt the medicine Tramadol is expensive, and the medicine is not expensive. The results are mixed. The perception of the cost of the medicine to be expensive or not depends on the brand name of the medicine, country, and place where it is sold, and the affordability of the patient. You can choose a generic drug in the place of the branded drug to save the cost. The efficiency of the medicine will not vary if it is generic or a branded one.
| Visitors | % | ||
|---|---|---|---|
| Expensive | 1 | 100.0% | |
One visitor reported frequency of use
How often in a day do you take the medicine?Are you taking the Tramadol drug as prescribed by the doctor?
Few medications can be taken Twice in a day more than prescribed when the doctor's advice mentions the medicine can be taken according to frequency or severity of symptoms. Most times, be very careful and clear about the number of times you are taking the medication. The report of sdrugs.com website users about the frequency of taking the drug Tramadol is mentioned below.
| Visitors | % | ||
|---|---|---|---|
| Twice in a day | 1 | 100.0% | |
Seventeen visitors reported doses
What is the dose of Tramadol drug you are taking?According to the survey conducted among sdrugs.com website users, the maximum number of people are using the following dose 51-100mg. Few medications come in only one or two doses. Few are specific for adult dose and child dose. The dose of the medicine given to the patient depends on the severity of the symptom/disease. There can be dose adjustments made by the doctor, based on the progression of the disease. Follow-up is important.
| Visitors | % | ||
|---|---|---|---|
| 51-100mg | 7 | 41.2% | |
| 11-50mg | 6 | 35.3% | |
| 1-5mg | 1 | 5.9% | |
| 101-200mg | 1 | 5.9% | |
| 201-500mg | 1 | 5.9% | |
| 501mg-1g | 1 | 5.9% | |
Five visitors reported time for results
What is the time duration Tramadol drug must be taken for it to be effective or for it to reduce the symptoms?Most chronic conditions need at least some time so the dose and the drug action gets adjusted to the body to get the desired effect. The stastistics say sdrugs.com website users needed 1 day to notice the result from using Tramadol drug. The time needed to show improvement in health condition after using the medicine Tramadol need not be same for all the users. It varies based on other factors.
| Visitors | % | ||
|---|---|---|---|
| 1 day | 2 | 40.0% | |
| 1 month | 1 | 20.0% | |
| > 3 month | 1 | 20.0% | |
| 3 days | 1 | 20.0% | |
Two visitors reported administration
The drugs are administered in various routes, like oral or injection form. They are administered before food or after food. How are you taking Tramadol drug, before food or after food?Click here to find out how other users of our website are taking it. For any doubts or queries on how and when the medicine is administered, contact your health care provider immediately.
| Visitors | % | ||
|---|---|---|---|
| After food | 1 | 50.0% | |
| With a meal | 1 | 50.0% | |
Seven visitors reported age
| Visitors | % | ||
|---|---|---|---|
| > 60 | 5 | 71.4% | |
| 46-60 | 2 | 28.6% | |
Visitor reviews
There are no reviews yet. Be the first to write one! |
The information was verified by Dr. Rachana Salvi, MD Pharmacology