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DRUGS & SUPPLEMENTS
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Limovan
How old is patient? |
Limovan uses
Pharmacological action
Limovan is a sleeping drug from group of cyclopyrrolone derivatives. This drug is "non benzodiazepine" agonist of benzodiazepine receptors. Limovan also has sedative, anxiolytic, muscle-relaxing center, anticonvulsant and amnesic properties. Like a derivative of benzodiazepine Limovan enhances GABA-ergic processes in the brain, interacting with the benzodiazepine receptors, as a result of the increased sensitivity of GABA-receptors to the neurotransmitter. However, Limovan apparently interacts with other parts of the benzodiazepine receptor than benzodiazepines.
Limovan reduced sleep time, reduces the number of nighttime awakenings, increases total sleep time. This medication almost has no effect on sleep structure, does not reduce significantly the amount of REM sleep. Consequences of the phenomenon of waking up are missing or expressed little. Readmission Limovan are not accompanied by cumulation.
Pharmacokinetics
Limovan rapidly and completely absorbed from the gastrointestinal tract. Cmax achieved within 1-3 hours. Limovan easily passes through gistogematicheskie barriers including the BBB and it is distributed in organs and tissues including brain. T1/2 is 5.5-6 hours, not accumulates.
Why is Limovan prescribed?
Sleep disturbance, transient, situational or chronic insomnia; sleep disturbances in mental disorders, bronchial asthma with nocturnal seizures (in combination with single dose daily dose of theophylline).
Dosage and administration
The average therapeutic dose of Limovan is 7.5 mg orally at night, in cases of severe insomnia the dose can be increased up to 15 mg. In elderly patients, as well as abnormal liver function is used 3.75 mg.
Limovan side effects, adverse reactions
Digestive system: a feeling of bitter or metallic taste in the mouth, dry mouth, nausea, and vomiting.
CNS: dizziness, headache, drowsiness, confusion, anterograde amnesia, hallucinations, nightmares.
Dermatologic reactions: skin rash.
Limovan contraindications
Severe respiratory failure, pregnancy, lactation, children and teens under 15 years old, hypersensitivity to Limovan.
Using during pregnancy and breastfeeding
Limovan is contraindicated during pregnancy (especially in I and III trimester) and lactation (breastfeeding). If a woman uses Limovan in III trimester of pregnancy there are possible violations of the nervous system in the newborn, the emergence of withdrawal syndrome. If the woman is prescribed by a doctor took Limovan immediately prior to labor and delivery, it needs a constant medical surveillance for the newborn. At the time of treatment it should be stoped breastfeeding (zopiclone penetrates into breast milk).
Special instructions
With caution use in patients with severe liver failure.
Risk of drug dependence is minimal if the duration of Limovan did not exceed 4 weeks. However, the potential danger of Limovan dependence to exist.
During the period of treatment patients should to exclude the use of alcohol.
On the next day after taking the drug it should be cautious to drive and operate machinery.
Limovan drug interactions
Simultaneous administration of Limovan with trimipramine reduces the concentration of trimipramine in plasma and its effect.
Limovan increases the influence of CNS depressants.
Limovan in case of emergency / overdose
Symptoms: CNS depression of varying severity (from drowsiness to loss of consciousness).
Treatment: gastric lavage, taking activated charcoal, if necessary - symptomatic therapy. As a specific antidote used benzodiazepine receptor antagonist flumazenil (in hospital). Hemodialysis is ineffective.
Limovan pharmaceutical active ingredients containing related brand and generic drugs:
Limovan available forms, composition, doses:
Limovan destination | category:
Limovan Anatomical Therapeutic Chemical codes:
Limovan pharmaceutical companies:
References
- "zopiclone". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
- "zopiclone". http://www.drugbank.ca/drugs/DB0119... (accessed August 28, 2018).
- "zopiclone: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/... (accessed August 28, 2018).
Frequently asked Questions
Can i drive or operate heavy machine after consuming Limovan?Depending on the reaction of the Limovan after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Limovan not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.
Is Limovan addictive or habit forming?Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
Review
sdrugs.com conducted a study on Limovan, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Limovan consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.Visitor reports
Visitor reported useful
No survey data has been collected yetVisitor reported side effects
No survey data has been collected yetOne visitor reported price estimates
What is your opinion about drug cost? Did you feel the cost is apt, or did you feel it is expensive?The report given by the sdrugs.com website users shows the following figures about several people who felt the medicine Limovan is expensive, and the medicine is not expensive. The results are mixed. The perception of the cost of the medicine to be expensive or not depends on the brand name of the medicine, country, and place where it is sold, and the affordability of the patient. You can choose a generic drug in the place of the branded drug to save the cost. The efficiency of the medicine will not vary if it is generic or a branded one.
| Visitors | % | ||
|---|---|---|---|
| Expensive | 1 | 100.0% | |
Visitor reported frequency of use
No survey data has been collected yetFour visitors reported doses
What is the dose of Limovan drug you are taking?According to the survey conducted among sdrugs.com website users, the maximum number of people are using the following dose 6-10mg. Few medications come in only one or two doses. Few are specific for adult dose and child dose. The dose of the medicine given to the patient depends on the severity of the symptom/disease. There can be dose adjustments made by the doctor, based on the progression of the disease. Follow-up is important.
| Visitors | % | ||
|---|---|---|---|
| 6-10mg | 2 | 50.0% | |
| 1-5mg | 1 | 25.0% | |
| 11-50mg | 1 | 25.0% | |
Two visitors reported time for results
What is the time duration Limovan drug must be taken for it to be effective or for it to reduce the symptoms?Most chronic conditions need at least some time so the dose and the drug action gets adjusted to the body to get the desired effect. The stastistics say sdrugs.com website users needed 2 weeks to notice the result from using Limovan drug. The time needed to show improvement in health condition after using the medicine Limovan need not be same for all the users. It varies based on other factors.
| Visitors | % | ||
|---|---|---|---|
| 2 weeks | 1 | 50.0% | |
| > 3 month | 1 | 50.0% | |
Visitor reported administration
No survey data has been collected yetVisitor reported age
No survey data has been collected yetVisitor reviews
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The information was verified by Dr. Rachana Salvi, MD Pharmacology