Calcrem

Calcrem uses

• Pharmacological action
• Pharmacokinetics
• Why is Calcrem prescribed?
• Dosage and administration
• Calcrem side effects, adverse reactions
• Calcrem contraindications
• Using during pregnancy and breastfeeding
• Special instructions
• Calcrem drug interactions
• Calcrem in case of emergency / overdose
• Calcrem reviews

Pharmacological action

Calcrem is an antifungal agent of imidazole derivatives group for topical use. This medication has an effect at the expense of the synthesis of ergosterol, which is part of the cell membrane of fungi. Calcrem has a broad spectrum of action.

Calcrem is active against dermatophytes, molds, fungi of the genus Candida, Malassezia furfur.

This drug is also active against Corynebacterium minutissimum, Streptococcus spp., Staphylococcus spp., Trichomonas vaginalis.

Pharmacokinetics

For external use Calcrem is well into the various layers of the skin reaching therapeutic concentrations. When this medication applied topically a small amount of it absorbed into the bloodstream.

Why is Calcrem prescribed?

Fungal skin and mucous membranes: ringworm, tinea, trichophytosis, athlete, mikrosporiya, candidiasis, a fungal interdigital erosion, fungal paronychia; fungal infections complicated by a secondary pyoderma; colorful lichen, erythrasma; thrush; Candida vulvitis, vulvovaginitis, balanitis, trichomoniasis; for the renovation of the birth canal before delivery.

Dosage and administration

When Calcrem used externally it applied to affected skin 2-3 times / day in 2-4 weeks.

For local orally this medicine used 1-2 times / day, no more than 7 days.

Intravaginal - on 100-500 mg for 1-6 days.

Calcrem side effects, adverse reactions

Local reactions: contact allergic dermatitis, redness, burning sensation.

When applied topically to the skin: erythema, blisters, swelling, burning and tingling, irritation and flaking skin.

When applied topically for the treatment of urogenital infections: itching, burning, redness and swelling of the mucous membrane, vaginal discharge, frequent urination, intercurrent cystitis, burning sensation in the penis with a partner, pain during sexual intercourse.

When applied topically in the oral cavity: redness of the oral mucosa, burning sensation and tingling at the site of application, irritation.

Calcrem contraindications

Hypersensitivity to Calcrem, I trimester of pregnancy.

Using during pregnancy and breastfeeding

In experimental studies there have been found that Calcrem used in high doses exerts embryotoxic effect.

It is not known whether Calcrem released in breast milk. Although Calcrem is not contraindicated during pregnancy and lactation, it should be considered a potential risk when selecting antifungal therapy.

Special instructions

Prescribed intravaginal Dosage forms of Calcrem is not used during menstruation.

To prevent reinfection it should be simultaneous treatment of sexual partners.

Calcrem is not recommended for use in ophthalmology.

Calcrem drug interactions

Simultaneous administration of Calcrem with amphotericin B, nystatin, natamycin activity of Calcrem decreases.

Calcrem in case of emergency / overdose

Symptoms: anorexia, nausea, vomiting, stomachodynia, abnormal liver function, rarely - drowsiness, hallucinations, thamuria, allergic skin reactions.

Treatment: taking activated charcoal, symptomatic therapy.

Calcrem pharmaceutical active ingredients containing related brand and generic drugs:

• Clotrimazole

Calcrem available forms, composition, doses:

• Cream; Topical; Clotrimazole 1%

Calcrem destination | category:

• Human:
• Anti-inflammatory agents
• Antifungals
• Azoles
• Mouth / throat preparations
• Non-steroidal antiinflammatory and antirheumatic products
• Nonsteroidal anti-inflammatory drugs (NSAIDs)
• Preparations for vaginal conditions
• Topical anti-infectives with corticosteroids
• Topical antifungals and antiparasites
• Treatment of inflammation and rheumatism

Calcrem Anatomical Therapeutic Chemical codes:

• A01AB18 - Clotrimazole
• D01AC01 - Clotrimazole
• G01AF02 - Clotrimazole

Calcrem pharmaceutical companies:

• Raptakos Brett

References

1. Dailymed."GYNE-LOTRIMIN 3 (CLOTRIMAZOLE) CREAM [MSD CONSUMER CARE, INC.]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
2. Dailymed."BETAMETHASONE DIPROPIONATE; CLOTRIMAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
3. "clotrimazole". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

Frequently asked Questions

Depending on the reaction of the Calcrem after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Calcrem not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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The information was verified by Dr. Rachana Salvi, MD Pharmacology