DRUGS & SUPPLEMENTS

Temonat

Name: Temonat drug & pharmaceuticals. Temonat available forms, doses, prices
Creator: sdrugs.com
Published: 2021-11-11T10:10:10+00:00

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Temonat uses

Temonat reviews

Temonat (Temodar and Temodal) is an oral alkylating agent used for the treatment of refractory anaplastic astrocytoma - a type of cancerous brain tumor. Temonat is not active until it is converted at physiologic pH to the active form, 5(3-methyltriazen-1-yl)imidazole-4-carboxamide (MTIC).

Indication: For the treatment of adult patients diagnosed with anaplastic astrocytoma whose disease has progressed after therapy with nitrosourea and procarbazine, as well as concomitantly with radiation therapy for treatment of newly diagnosed glioblastoma multiforme. Also used as maintenance therapy for glioblastoma multiforme.

Temonat is an imidazotetrazine deritave and an antineoplastic agent. It is a prodrug that has little to no pharmacological activity until it is hydrolyzed in vivo to 5-(3-methyltriazen-1-yl)imidazole-4-carboxamide (MTIC). After administration, Temonat undergoes rapid, nonenzymatic hydrolysis at physiological pH to MTIC, which is the active form of the drug. MTIC is generated through the effect of water at the highly electropositive C4 position of Temonat, causing the ring of Temonat to open, release carbon dioxide, and generate MTIC.

Temonat pharmaceutical active ingredients containing related brand and generic drugs:

Temozolomide

Temonat available forms, composition, doses:

Capsules; Oral; Temozolomide 100 mg
Capsules; Oral; Temozolomide 20 mg
Capsules; Oral; Temozolomide 250 mg

Temonat destination | category:

Human:
Antineoplastic agents
Cytotoxic chemotherapy

Temonat Anatomical Therapeutic Chemical codes:

L01AX03 - Temozolomide

Temonat pharmaceutical companies:

Natco Pharma

References

Dailymed."TEMOZOLOMIDE CAPSULE [SUN PHARMA GLOBAL FZE]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
Dailymed."TEMOZOLOMIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
"temozolomide". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Temonat?

Depending on the reaction of the Temonat after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Temonat not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Temonat addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

Review

sdrugs.com conducted a study on Temonat, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Temonat consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.