DRUGS & SUPPLEMENTS

Duromine

Name: Duromine drug & pharmaceuticals. Duromine available forms, doses, prices
Creator: sdrugs.com
Published: 2021-11-11T10:10:10+00:00

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Duromine uses

What is Duromine?
Pharmacological action
Why is Duromine prescribed?
Dosage and administration
Duromine side effects, adverse reactions
Contraindications
Duromine using during pregnancy and breastfeeding
Special instructions
Duromine drug interactions
Duromine in case of emergency / overdose
Duromine reviews

What is Duromine?

Duromine is an appetite suppressant of a pharmacological group of amphetamines and phenethylamines. This medication was approved to help reduce weight in obese patients for short-term use and combination with exercise, diet and behavior changes. It usually prescribed to individuals who have health risks due to their weight. This active ingredient Duromine is manufactured and distributed in various countries under different trade brand and generic names, for example: Adipex-P (Teva), Ionamin (Celltech), Acxion (Investigacion Farmaceutica), Fastin (GlaxoSmithKline), Duromine (iNova, Douglas Pharmaceuticals), Panbesy (Eurodrug Laboratories), Duromine (KVK-TECH), Duromine (Eon Labs), etc. In several countries (such as the USA, Canada, Australia) this drug is a controlled substance because it can cause addiction.

Pharmacological action

Duromine acts on the brain neurotransmitters. Duromine is a central stimulant and an isomer of methamphetamine. It stimulates neurons to release a particular group of neurotransmitters known as catecholamines among which are dopamine, epinephrine (also called adrenaline) and norepinephrine. The appetite suppression activity of these compounds is due to its action on the central nervous system. This mechanism of action is similar to other stimulant appetite suppressants such as diethylpropion and phendimetrazine. The neurotransmitters signal the alert response which also stops the hunger.

Why is Duromine prescribed?

Duromine is used to reduce body weight in obese or overweight patients. Often it prescribed in a regimen of weight reduction based on exercise, behavioral modification, and caloric restriction in the management of exogenous obesity for obese or overweight patients with the presence of other risk factors. Duromine works by directly affecting the area of the brain that controls your appetite making you feel less hungry.

Dosage and administration

It is recommended to use Duromine only in the short term (usually about 12 weeks) and then other non-pharmacological strategies for weight loss and healthy dieting and exercise. However, recommendations limiting its use for short-term treatment are controversial. One reason for the restriction to 12 weeks is drug tolerance, as Duromine loses its appetite-suppressing effects after the body adjusts. On the contrary, it has been shown that this drug did not lose its effect in a trial of 36 weeks. Due to the risk of insomnia, it is recommended taking Duromine before breakfast or 1-2 hours later.

Duromine side effects, adverse reactions

Generally, Duromine is relatively well tolerated but can cause some side effects because it releases catecholamines. Among the most common effects include: tachycardia, elevated blood pressure, palpitations, nervousness, irritability and insomnia. Additionally, if Duromine is taken for long term, it may develop euphoria and addiction. Other less common side effects include blurred vision, changes in sex drive, clumsiness, confusion, diarrhea, dizziness, dry mouth, headache, irregular heartbeat, nausea or vomiting, psychosis, skin rash or itching, stomach pain, fatigue and bad taste.

Contraindications

The following people should not use Duromine:

Allergy to any ingredient of Duromine containing pharmaceutical form (usually capsules or tablets) or other sympathomimetic (eg, pseudoephedrine).

Taking dexfenfluramine, fenfluramine, furazolidone, guanadrel, guanethidine, or have taken of mono-amine oxidase inhibitors (MAOIs) (eg., phenelzine) in the last 14 days.

With high blood pressure or moderate hyperthyroidism, glaucoma, heart or circulatory disease, or severe narrowing of blood vessels.

Who are in a state of agitation or have a history of alcohol or drug abuse.

Duromine using during pregnancy and breastfeeding

There is no data whether Duromine can cause fetal harm when administered to a pregnant woman or can affect reproductive capacity. Thats why rgis drugs should be given to a pregnant woman only if clearly needed.

Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Safety and effectiveness of Duromine in pediatric patients have not been established.

Special instructions

You healthcare professional should be informed of the following conditions:

If you are pregnant or plan to become pregnant or if you are breastfeeding (lactation).

If you are taking prescription or nonprescription medications, herbal preparations or dietary supplements.

If you have allergies to medicines, foods or other substances.

If you have a brain disorder or spinal cord, narrowing of the arteries, high blood pressure (hypertension), diabetes or high cholesterol or lipids.

Duromine drug interactions

The following drugs can interact with Duromine Quality Pharmaceutical Laboratory:

Dexfenfluramine, fenfluramine, furazolidone, or inhibitors of MAO (eg., phenelzine) because the risk of serious side effects such as headaches, high blood pressure, low pulse, elevated temperature or fatal lung problems.

Inhibitors of serotonin reuptake (such as fluoxetine).

Guanadrel or guanethidine because their effectiveness may be decreased by Duromine.

Duromine in case of emergency / overdose

In case of overdose of Duromine Quality Pharmaceutical Laboratory, call your local poison control center or local emergency services.

Manifestations of acute overdosage with Duromine include restlessness, hyperreflexia, tremor, confusion, assaultiveness, rapid respiration, hallucinations, panic states. Fatigue and depression usually follow the central stimulation. Cardiovascular effects include hypertension or hypotension, arrhythmia, and circulatory collapse. Gastrointestinal symptoms include vomiting, nausea, diarrhea and abdominal cramps. Fatal poisoning usually terminates in convulsions and coma.

Management of acute Duromine intoxication is largely symptomatic and includes lavage and sedation with a barbiturate. Hemodialysis or peritoneal dialysis is ineffective and not recommended in this regard.

Duromine pharmaceutical active ingredients containing related brand and generic drugs:

Phentermine

Duromine available forms, composition, doses:

Capsules, Sustained Release; Oral; Phentermine 15 mg
Capsules, Sustained Release; Oral; Phentermine 30 mg
Capsules; Oral; Phentermine 15 mg
Capsules; Oral; Phentermine 30 mg
Capsules; Oral; Phentermine 40 mg

Duromine destination | category:

Human:
Amphetamines
Anorexigenic agents and respiratory and cerebral stimulants
Anti-obesity agents
Appetite suppressants
Phenethylamines
Psychostimulant drugs

Duromine Anatomical Therapeutic Chemical codes:

A08AA01 - Phentermine

Duromine pharmaceutical companies:

References

"phentermine". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
"phentermine". http://www.drugbank.ca/drugs/DB0019... (accessed August 28, 2018).
"C045TQL4WP: The UNique Ingredient Identifier (UNII) is an alphanumeric substance identifier from the joint FDA/USP Substance Registration System (SRS).". https://www.fda.gov/ForIndustry/Dat... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Duromine?

Depending on the reaction of the Duromine after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Duromine not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Duromine addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

Review

sdrugs.com conducted a study on Duromine, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Duromine consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.