DRUGS & SUPPLEMENTS

Multiparin

Name: Multiparin drug & pharmaceuticals. Available Forms, Doses, Prices
Creator: sdrugs.com
Published: 2021-11-11T10:10:10+00:00

Rating: 1 - 1 review(s)

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Multiparin uses

Multiparin reviews

Unfractionated Multiparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight Multiparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated Multiparin is more specific than LMWH for thrombin. Furthermore, the effects of UH can typically be reversed by using protamine sulfate.

Indication: Unfractionated Multiparin is indicated for prophylaxis and treatment of venous thrombosis and its extension, prevention of post-operative deep venous thrombosis and pulmonary embolism and prevention of clotting in arterial and cardiac surgery. In cardiology, it is used to prevent embolisms in patients with atrial fibrillation and as an adjunct antithrombin therapy in patients with unstable angina and/or non-Q wave myocardial infarctions (i.e. non-ST elevated acute coronary artery syndrome) who are on platelet glycoprotein (IIb/IIIa) receptor inhibitors. Additionally, it is used to prevent clotting during dialysis and surgical procedures, maintain the patency of intravenous injection devices and prevent in vitro coagulation of blood transfusions and in blood samples drawn for laboratory values.

Unfractionated Multiparin is a highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from 3000 to 30,000 daltons. Multiparin is obtained from liver, lung, mast cells, and other cells of vertebrates. Multiparin is a well-known and commonly used anticoagulant which has antithrombotic properties. Multiparin inhibits reactions that lead to the clotting of blood and the formation of fibrin clots both in vitro and in vivo. Small amounts of Multiparin in combination with antithrombin III, a Multiparin cofactor,) can inhibit thrombosis by inactivating Factor Xa and thrombin. Once active thrombosis has developed, larger amounts of Multiparin can inhibit further coagulation by inactivating thrombin and preventing the conversion of fibrinogen to fibrin. Multiparin also prevents the formation of a stable fibrin clot by inhibiting the activation of the fibrin stabilizing factor. Multiparin prolongs several coagulation tests. Of all the coagulation tests, activated partial prothrombin time (aPTT) is the most clinically important value.

Multiparin pharmaceutical active ingredients containing related brand and generic drugs:

Heparin Sodium

Multiparin available forms, composition, doses:

Multiparin destination | category:

Human:
Anticoagulants, antiplatelets and fibrinolytics (thrombolytics)
Heparins
Phlebitis and varicose preparations

Multiparin Anatomical Therapeutic Chemical codes:

B01AB01 - Heparin
C05BA03 - Heparin
S01XA14 - Heparin

Multiparin pharmaceutical companies:

References

Dailymed."HEPARIN SODIUM INJECTION [SAGENT PHARMACEUTICALS]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
"heparin". https://pubchem.ncbi.nlm.nih.gov/su... (accessed August 28, 2018).
"Heparin - DrugBank". http://www.drugbank.ca/drugs/DB0110... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Multiparin?

Depending on the reaction of the Multiparin after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Multiparin not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Multiparin addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

Review

sdrugs.com conducted a study on Multiparin, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Multiparin consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.