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DRUGS & SUPPLEMENTS
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Lupenox
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Lupenox uses
Lupenox is a low molecular weight heparin. Lupenox is used to prevent and treat deep vein thrombosis or pulmonary embolism, and is given as a subcutaneous injection. Lupenox binds to and accelerates the activity of antithrombin III. By activating antithrombin III, Lupenox preferentially potentiates the inhibition of coagulation factors Xa and IIa. Factor Xa catalyzes the conversion of prothrombin to thrombin, so enoxaparin’s inhibition of this process results in decreased thrombin and ultimately the prevention of fibrin clot formation. Low molecular weight heparins are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin.
Indication: For the prophylaxis of deep vein thrombosis, which may lead to pulmonary embolism, and also for the prophylaxis of ischemic complications of unstable angina and non-Q-wave myocardial infarction, when concurrently administered with aspirin.
Lupenox is a highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from 3800 to 5000 daltons. Lupenox occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Lupenox is a well known and commonly used anticoagulant which has antithrombotic properties. Lupenox inhibits reactions that lead to the clotting of blood and the formation of fibrin clots both in vitro and in vivo. Lupenox acts at multiple sites in the normal coagulation system. Small amounts of Lupenox in combination with antithrombin III (enoxaparin cofactor) can inhibit thrombosis by inactivating activated Factor X and inhibiting the conversion of prothrombin to thrombin. Once active thrombosis has developed, larger amounts of Lupenox can inhibit further coagulation by inactivating thrombin and preventing the conversion of fibrinogen to fibrin. Lupenox also prevents the formation of a stable fibrin clot by inhibiting the activation of the fibrin stabilizing factor. Its use should be avoided in patients with a creatinine clearance less than 20mL/min. In these patients, unfractionated heparin should only be used. As for monitoring, active partial thromboplastin time (aPTT) will only increase at high doses of low molecular weight heparins (LMWH). Therefore, monitoring aPTT is not recommended. However, anti-Xa activity can be measured to monitor the efficacy of the LMWH.
Lupenox pharmaceutical active ingredients containing related brand and generic drugs:
Lupenox available forms, composition, doses:
Lupenox destination | category:
Lupenox Anatomical Therapeutic Chemical codes:
Lupenox pharmaceutical companies:
References
- "enoxaparin". https://pubchem.ncbi.nlm.nih.gov/su... (accessed August 28, 2018).
- "Enoxaparin - DrugBank". http://www.drugbank.ca/drugs/DB0122... (accessed August 28, 2018).
Frequently asked Questions
Can i drive or operate heavy machine after consuming Lupenox?Depending on the reaction of the Lupenox after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Lupenox not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.
Is Lupenox addictive or habit forming?Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
Review
sdrugs.com conducted a study on Lupenox, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Lupenox consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.Visitor reports
Visitor reported useful
No survey data has been collected yetVisitor reported side effects
No survey data has been collected yetVisitor reported price estimates
No survey data has been collected yetVisitor reported frequency of use
No survey data has been collected yetOne visitor reported doses
What is the dose of Lupenox drug you are taking?According to the survey conducted among sdrugs.com website users, the maximum number of people are using the following dose 6-10mg. Few medications come in only one or two doses. Few are specific for adult dose and child dose. The dose of the medicine given to the patient depends on the severity of the symptom/disease. There can be dose adjustments made by the doctor, based on the progression of the disease. Follow-up is important.
| Visitors | % | ||
|---|---|---|---|
| 6-10mg | 1 | 100.0% | |
Three visitors reported time for results
What is the time duration Lupenox drug must be taken for it to be effective or for it to reduce the symptoms?Most chronic conditions need at least some time so the dose and the drug action gets adjusted to the body to get the desired effect. The stastistics say sdrugs.com website users needed 5 days to notice the result from using Lupenox drug. The time needed to show improvement in health condition after using the medicine Lupenox need not be same for all the users. It varies based on other factors.
| Visitors | % | ||
|---|---|---|---|
| 5 days | 2 | 66.7% | |
| 3 month | 1 | 33.3% | |
One visitor reported administration
The drugs are administered in various routes, like oral or injection form. They are administered before food or after food. How are you taking Lupenox drug, before food or after food?Click here to find out how other users of our website are taking it. For any doubts or queries on how and when the medicine is administered, contact your health care provider immediately.
| Visitors | % | ||
|---|---|---|---|
| Empty stomach | 1 | 100.0% | |
Visitor reported age
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The information was verified by Dr. Rachana Salvi, MD Pharmacology